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New techniques in liver surgery
(2006-01-20)
The development of liver surgery has a long history and through the years, much knowledge has been gathered concerning various aspects of the liver. The exploration and understanding of liver anatomy and liver regeneration ...
Drug use among the very old living in ordinary households : aspects on well-being, cognitive and functional ability
(2007-02-28)
Background: In Sweden today a major proportion of the population survive to old ages. To a large extent, the oldest old are capable of living longer in their own households; some of them are very healthy while others have ...
Genetic epidemiological studies of adverse pregnancy outcomes and the role of schizophrenia
(2006-02-24)
The purposes of this thesis were to investigate the importance of genetic and environmental factors in the development of adverse pregnancy outcomes and to investigate the role of schizophrenia as a risk factor for and a ...
Multiple sclerosis : MRI diagnosis, potential treatment and future potential for nanoparticle applications
(2005-10-10)
Multiple Sclerosis is an inflammatory demyelinating and neurodegenerative disease of the central nervous system. Magnetic resonance imaging is an important tool for diagnosing of Multiple Sclerosis and for, in vivo, ...
Organic dust-induced signaling in human pulmonary epithelial cells : emphasis on effects of cAMP modulation
(2005-09-09)
To study signaling transductions in innate immunity a model system was applied where A549 alveolar epithelial type II cells were used as target and organic dust collected in swine confinement buildings as stimulus. The ...
Mechanisms of liver allograft rejections
(2005-05-20)
Liver transplantation (M) has become a standard treatment for many end-stage liver diseases. However, acute rejections still occur in about half of the liver transplant recipients even treated with a combination of different ...
Role of the OX40 ligand/receptor pair in coronary artery disease
(2006-11-17)
Atherosclerosis is the pathological basis for coronary artery disease (CAD), the leading cause of morbidity and mortality in developed countries. CAD and atherosclerosis have long been known to have a familial component ...
Locally recurrent rectal cancer : aspects on management, surgery and outcome
(2017-11-01)
intent. Five-year survival was 23% for patients treated with curative intent and 9% for all LRRC patients. The results present a congruence between factors predictive for treatment and prognostic factors, indicating an adequate selection for treatment...
p53 transcriptional activity as a tool to uncover novel and diverse druggable targets in cancer
(2018-05-28)
The transcription factor p53 is one of the most studied tumour suppressors with over 90 000 publications in PubMed referring to the protein. It is also the most frequently mutated gene across all cancer types with around ...