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Humeral shaft fractures : epidemiology outcome
(2007-10-26)
Humeral shaft fractures account for 1-3% of all fractures and
approximately 20% of all humeral fractures. Non-operative treatment with
functional bracing has been regarded as the golden standard for treatment
of closed ...
Clinical and economic features of categories of patients in defined populations
(2005-11-18)
This thesis addresses the use of information from health care registers on an individual level, making it possible to elucidate the morbidity and comorbidity patterns in defined populations, and to allocate resources in ...
Studies on polyomavirus virus-like particles : as vaccines and vectors for immune and gene therapy
(2006-03-10)
Virus-like particles (VLPs) are similar to natural virus particles except that they lack viral genes. They have a similar cellular uptake to the natural virus from which they are derived but are non-infectious and can ...
Vocational rehabilitation, work resumption and disability pension : a register-study of cases granted vocational rehabilitation by social insurance offices in a Swedish county
(2006-02-03)
Increasing figures for long-term sickness absence and disability pension are problems for many European countries where they have increased to burdensome levels, socially and financially. In a European study in 2003, Sweden ...
Effects of joint cocaine and ethanol on the brain opioid systems
(2005-10-11)
Concurrent abuse of cocaine and alcohol is common among human addicts, where 85% of all cocaine users have also been shown to meet the criteria for alcohol dependence. Concurrent abuse of cocaine and alcohol is associated ...
A modular mRNA approach to study and treat phospholamban mediated cardiomyopathies
(2022-05-30)
In the heart, phospholamban (PLN) is a key regulator of calcium cycling through its inhibitory effect on the sarco/endoplasmic reticulum Ca2+-ATPase (SERCA) pump. For more than two decades, modulating calcium channels has ...
Regulation of vaccine immunity : from myeloid cell functions to antibody responses
(2019-12-05)
The generation of vaccine-induced protection against infections relies on a well-coordinated network of innate immune responses, adaptive cellular responses, and humoral responses. Sufficient stimulation of the innate ...
Guillain-Barré syndrome : disability, quality of life, illness experiences and use of healthcare
(2006-10-27)
, 16 patients (38%) had a pre-existing illness, 36 patients (86%) had immunomodulatory treatment in the acute phase, and nine patients (21 %) required ventilator support for 5-287 days (Papers I-III). Most significant improvement in muscular speed...
Selenium compounds as a novel class of experimental cancer chemotherapeutics
(2021-02-25)
Selenium is an essential micronutrient for humans, it has a narrow margin between antioxidant and pro-oxidant effects. Redox-active selenium compounds have the potency to increase ROS levels in cancer cells, providing a ...
Factors affecting alcohol self-administration : learning, environmental and genetic influences on behaviour
(2006-09-05)
with ethanol) to observe what affect this would have on subsequent alcohol self-administration. When rats were subjected to a 5-minute delay, active lever press response increased by 26% and consumption of ethanol (via blood alcohol measurements) significantly...