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Estrogen in the development of esophageal and gastric adenocarcinoma
(2007-11-23)
”, the intestinal type of gastric AC was over 4 and 9 times more common among “unexposed men” (OR 4.7; 95% CI 2.2-10.3) and “unexposed women” (OR 9.1; 95% CI 4.3-19.6), respectively. No differences in ER expression were found between the three groups. A loss...
Statistical methodology for testing genetic association in family-based studies
(2008-04-25)
This thesis is concerned with family-based studies of association between genetic markers and binary traits. A special point of interest in family-based association studies is to separate the within family correlation and ...
Human serum transferrin glycosylation pattern : population differences, analytical methodology and application as a biomarker for testing of alcohol abuse and CDG
(2007-11-16)
Alcohol use and abuse is a major social and economic problem in many
societies. Carbohydrate-deficient transferrin (CDT) is a widely used and
highly specific biochemical alcohol marker of prolonged alcohol abuse.
Increased ...
Rehabilitation after anterior cruciate ligament reconstruction using patellar tendon or hamstring grafts : open and closed kinetic chain exercises
(2007-03-02)
for Sport/Rec KOOS and QOL KOOS. Patellar tendon graft in favor of hamstring tendon graft and a short time (< 6 months) between injury and ACL surgery partly explained a higher level of activity (TAS). Absence of cartilage damage explained 6 % of good...
Studies of preoperative evaluation and surgical procedures for gastroesophageal reflux disease
(2006-11-10)
Introduction: Gastroesophageal reflux disease (GERD) is defined as the non-physiological movement of gastric contents from the stomach to the esophagus, which causes various degrees of troublesome symptoms and/or esophageal ...
Epidemiological studies on complications in type 1 diabetes
(2008-03-14)
The main threat to the health of patients with type 1 diabetes (T1DM) is its complications. This thesis aimed to assess the risks of hip fracture, non-trauma lower extremity amputation (LEA) and myocardial infarction in ...
Testosterone and the postmenopausal breast : aspects on cell proliferation and mammographic density
(2008-04-04)
The breast is a target organ for sex steroids, and hormonal treatments
have been associated with a risk of breast cancer. There is increasing
interest in androgen treatment for postmenopausal women. Testosterone has
been ...
Pregnancy rhinitis : pathophysiological effects of oestrogen and treatment with oral decongestants
(2007-10-19)
Pregnancy rhinitis, a common condition, is thought to affect about 20 %
of pregnant women. This type of rhinitis may develop at any time during
pregnancy and the nasal stuffiness usually disappears shortly after
delivery. ...
Glutamine to ICU patients
(2007-11-16)
Intravenous glutamine supplementation to intensive care patients using a
glutamine containing dipeptide is now widely accepted in clinical
practice. There are evidences that glutamine supplementation of ICU
patients in ...
Paediatric burn injuries in Cape Town, South Africa : context, circumstances, and prevention barriers
(2007-05-03)
Despite concerns about the impact of childhood burns, there remains a
paucity of systematic descriptions of its epidemiology, contexts of
occurrence, and preventability. This information is essential for the
development ...