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Anterior cruciate ligament injury : factors affecting selection of treatment and intermediate outcome
(2006-11-17)
score, the Visual Analogue Scale (VAS) 0-10, the KT-1 000 arthrometer and the Biodex System 3. Subjects who chose to undergo ACL reconstruction were asked to report the reasons relevant for their decision. At the six years follow-up the subjects...
Predictors of cognitive decline in memory clinic patients
(2007-05-18)
Background: The major challenge in memory clinics is to predict
development as well as non-development of dementia among the
heterogeneous group of patients with cognitive complaints. Since the
advent of pharmacological ...
Statistical methodology for testing genetic association in family-based studies
(2008-04-25)
This thesis is concerned with family-based studies of association between genetic markers and binary traits. A special point of interest in family-based association studies is to separate the within family correlation and ...
Fixed-dose chloroquine and sulfadoxine/pyrimethamine treatment of malaria : outcome and pharmacokinetic aspects
(2007-04-06)
Background: A pre-packaged fixed-dose formulation of chloroquine (CQ) and
sulfadoxine/pyrimethamine (SIP) combination (Homapak) is widely used for
the treatment of falciparum malaria in the Home Based Management of
Fevers ...
Microfluidic electrocapture in proteomic sample preparation for mass spectrometry
(2007-10-19)
Proteomics is a technology-driven discipline and very labor-intensive.
Over the last couple of years, methods with microfluidic systems have
been used to simplify analytical procedures via integration of laboratory
processes ...
Serum proteins in type 1 diabetes
(2007-01-05)
We have previously shown that there are patients with type 1 diabetes T1D
whose sera interfere with cytoplasmic free Ca2+-concentration ([Ca2+]i),
resulting in â-cell apoptosis. In this study the frequency of sera, ...
Human C-reactive protein : genetic and hormonal regulation and role in atherogenesis
(2007-03-23)
Although in decline in the developed world CHD is still the number one
killer. The decline is thought to be due to better risk prevention and
treatment. C-reactive protein (CRP) has emerged as an marker of CHD. It
is ...
Human serum transferrin glycosylation pattern : population differences, analytical methodology and application as a biomarker for testing of alcohol abuse and CDG
(2007-11-16)
Alcohol use and abuse is a major social and economic problem in many
societies. Carbohydrate-deficient transferrin (CDT) is a widely used and
highly specific biochemical alcohol marker of prolonged alcohol abuse.
Increased ...
Rheumatoid arthritis as a modifier of periodontitis
(2007-01-19)
Periodontitis is a chronic tissue-destructive condition in which the
tooth-supporting collagen fibers of ligament and bone are broken down
mainly by the host s overreactive immune inflammatory response. The
relation between ...
Development of dementia in mild cognitive impairment (MCI) patients with focus on B-vitamins
(2007-05-04)
This thesis focused on the importance of low B-vitamins, hyperhomocysteinemia and the development of dementia and Alzheimer´s disease (AD) in patients with mild cognitive impairment (MCI). The relation between vitamin B12 ...