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Opioids and regulation of breathing
(2004-10-29)
.22 mg/kg FF, 0.44 mg/kg M-high and 0.11 mg/kg M-low. Sodium chloride 9 mg/ml was used as placebo. Blood was collected and plasma concentration analysed for frakefamide, morphine and its metabolites.
All studies were performed in healthy volunteers...
Pain treatment after surgery : with special reference to patient-controlled analgesia, early extubation and the use of paracetamol
(2004-11-26)
The introduction of general anaesthesia eliminated pain during surgical
operations. After surgery, however, pain and postoperative nausea and
vomiting (PONV) have remained a persistent problem for many patients. The
need ...
Cellular and molecular mechanisms in abdominal aortic aneurysm growth and rapture
(2005-11-11)
-degrading proteases in the AAA wall. Gene arrays and quantitative real-time PCR showed that matrix metalloproteinase (MMP)-1, -7, -9 and -12 mRNA expressions were upregulated in the thrombus-free wall compared with the thrombus-covered wall. Immunohistochemistry...
Inhaled sedation with isoflurane in the intensive care unit
(2006-10-06)
Patients in the Intensive Care Unit (ICU) may experience distress and pain, for which they are often prescribed sedative and analgesic drugs, sometimes at the cost of clinically significant side effects, such as prolonged ...
Anxiety, exhaustion and depression in relation to periodontal diseases
(2006-03-10)
level in GCF was increased, whereas the patients in Study IV surprisingly showed lower cortisol values in GCF than the controls. The level of cortisol in saliva was similar in both groups. Neither did the levels of matrix metalloproteinases-8, -9 (MMP-8...
The role of incretin peptides and ghrelin in upper gut motility and metabolic control
(2006-11-24)
Metabolic control is essential for the individual and is strictly regulated via a wide range of factors. One important mechanism in maintaining an adequate blood sugar level is the regulation of insulin release and gastric ...
The study of sensory cilia development in Caenorhabditis elegans
(2008-01-04)
Cilia and flagella are widespread eukaryotic subcellular components
that are conserved from green algae to mammals. In different organisms
they function in cell motility, movement of extracellular fluids and
sensory ...
Orthology and protein domain architecture evolution
(2006-05-22)
A major factor behind protein evolution is the ability of proteins to evolve new domain architectures that encode new functions. Protein domains are widely considered to constitute the "atoms" of protein chains, acting as ...
Uveal melanoma : epidemiological and clinical aspects
(2005-09-23)
A major purpose with this thesis was to assess the incidence and mortality rates of uveal melanoma in Sweden during the period 1960 to 1998, using population-based registry data.
In total, 2,995 patients (1,541 males ...
Diagnostic tests for adiposity and metabolic risk factors in adolescence : results from the Stockholm weight development study (SWEDES)
(2005-03-25)
Background: Despite growing concern about the development of pediatric
obesity, there is still controversy about its classification.
International classification systems have been proposed and national
systems are in ...