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Synthesis of indoles, bisindoles and indolocarbazoles : high affinity aryl hydrocarbon receptor ligands
(2004-09-03)
prepared in a Lewis acid mediated acylation involving different
indoles and indolyl-2-carbonyl chlorides. Synthesis of the metabolites
proved the assigned structures as 2-hydroxy-, 8-hydroxy-,
2,10-dihydroxy-, 4,8-dihydroxy- and 2,8dihydroxyindolo[3,2-b...
Cognitive functions in depression and anxiety disorders : findings from a population-based study
(2006-11-10)
This doctorial thesis examines cognitive functions in depression and anxiety disorders in a populationbased sample that includes mostly untreated persons. It is well established that depression is associated with cognitive ...
Assessment of anti-diabetic effect of Vietnamese herbal drugs
(2005-11-18)
The prevalence of type 2 diabetes mellitus is increasing in Vietnam as well as in other developing countries (China, Indian subcontinent, and Africa). Searching for hypoglycemic agents with origin from domestic herbals was ...
Asthma, chronic bronchitis, chronic obstructive pulmonary disease (COPD) and respiratory symptoms among adults in Estonia : prevalence and risk factors : comparison with Sweden and Finland : the 'FinEsS' studies Estonia I
(2005-11-04)
The thesis is based on original research data of the Estonian part of the
"FinEsS" studies, which are cross-sectional comparative studies between
Finland, Estonia and Sweden aiming to estimate the prevalence of
respiratory ...
Studies on alcoholic liver disease
(2006-11-17)
. Western blotting confirmed anti-human CYP2E 1 reactivity in 8 of 85 alcoholic sera, and 3 of 58 control sera. Anti-CYP3A4 reactivity was detected in 18 of 85 alcoholic sera and 4 of 58 control sera. The results suggest that autoantibodies toward both CYP2E...
Studies on polyomavirus virus-like particles : as vaccines and vectors for immune and gene therapy
(2006-03-10)
Virus-like particles (VLPs) are similar to natural virus particles except that they lack viral genes. They have a similar cellular uptake to the natural virus from which they are derived but are non-infectious and can ...
Regulation of non-responsiveness and death in cytotoxic T cells by the agonistic potency of MHC : peptide ligands
(2006-04-21)
CD8+ T lymphocytes are important for immunological control of infections and tumors. The key interaction required to initiate the process of T cell activation is the engagement of the T cell receptor (TCR) with a major histocompatibility complex...
On the development of postural adjustments in sitting and standing
(2006-10-27)
We have studied postural adjustments, i.e., muscle activity elicited by external perturbations in typically developing infants during the periods in life when independent sitting and standing emerge. We also studied two ...
Performance and trainability in paraplegics : motor function, shoulder muscle strength and sitting balance before and after kayak ergometer training
(2006-11-17)
Background: Spinal cord injury (SCI) results in a complete or partial loss of motor and/or sensory function below the injury level. An SCI causes extensive functional impairment compelling many persons to wheelchair usage. ...
Functional studies on the interaction of immunoglobulins with HIV-2 envelope
(2005-09-16)
by 7C8, while only gp125 oligomers were recognized by 3C4. Previous studies have demonstrated that HIV-1 binding to CD4 causes conformational changes in the envelope, where the V1 and V2 loops reorient and expose the V3 region. Surface plasmon resonance...