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Sleepiness : night work, time zones and activity
(2006-05-26)
Shift work and travel across time zones affect sleep and alertness negatively, and hence influence accident rate. Self-selected work hours, contextual, and environmental factors affect sleepiness, but it is unclear exactly ...
Endometrial, embryonic and ovarian aspects of human implantation
(2006-05-11)
cycle and in human ovary. After stimulation with TSH and thyroid hormone, endometrial epithelial and stromal cells showed increased cAMP (activation of TSHR) and ERK1/2 (activation of TR receptors) expression. Significant down-regulation of LIF gene...
Signaling to and from the sodium pump : effects of insulin and cardiotonic steroids
(2006-10-20)
by wortmannin and GF109203X. Insulin led to an increase in phosphorylation of the α1- and α2-subunits. C-peptide caused phosphorylation of the human α1-subunit on a Thr-Pro amino acid motif that confers a specific ERK phosphorylation site. ERK1 and 2 kinases...
Functional studies on the interaction of immunoglobulins with HIV-2 envelope
(2005-09-16)
Infection with HIV-2 has a much more limited geographic distribution than HIV-1, being less readily transmitted and is generally less pathogenic. The role of immunoglobulins in defence against pathogens in different body compartments is known, where...
The role of Nkx proteins neuronal and glial specification
(2004-11-12)
) are sequentially generated from a domain defined by the expression of Olig2. We show that the generation of sMNs and OLPs in the ventral spinal cord is essentially missing in mice lacking Nkx6 function. In contrast, the same HD proteins instead act to suppress OLP...
HIV-2 genetic evolution and viral dynamics
(2006-05-03)
HIV-2 is less pathogenic and less transmissible compared to HIV-1. This is believed to be due to the lower viral load that is seen in HIV-2 infected patients. However, why this lower viral load is seen is not known. In this thesis we have...
Assessment of anti-diabetic effect of Vietnamese herbal drugs
(2005-11-18)
The prevalence of type 2 diabetes mellitus is increasing in Vietnam as well as in other developing countries (China, Indian subcontinent, and Africa). Searching for hypoglycemic agents with origin from domestic herbals was considered as a useful way...
The role of angiomotin in endothelial cell motility and cell-cell junction formation
(2005-08-26)
that angiomotin belongs to a novel protein family with two additional members in human; angiomotin like 1 and angiomotin like 2. The protein family is characterized by a highly conserved coiled-coil motif, a C-terminal putative PDZ binding motif and an N...
Antibacterial effects of nitrite in urine
(2005-04-01)
Urinary tract infections (UTI`s) are among the most common conditions causing individuals to seek medical care. In addition, catheter-associated infections account for most of the hospital-acquired UTI´s and is also a major ...
Meeting ethical and nutritional challenges in elder care : the life world and system world of staff and high level decision-makers
(2006-10-27)
The overall aim of the thesis was to describe the issue of malnutrition and use it as a focal point of interest in elder care. A further aim was to illuminate how this issue could be addressed focusing on older adults' ...