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Biosynthesis of leukotriene B4 in hematological malignancies
(2005-05-27)
Leukotrienes (LT) are biologically active metabolites of the fatty acid
arachidonic acid (AA). After liberation of AA by phospholipase A 2 (PLA
2), this fatty acid can be converted to leukotrienes, lipoxins,
prostaglandins ...
Novel insulin-like growth factor-binding protein proteases : detection and characterization
(2006-10-07)
Members of the insulin-like growth factor (IGF) system are known to have an impact on cell differentiation, proliferation and survival, and to be important regulators for nutrient metabolism. The IGF-binding proteins ...
Incidence and prognosis of differentiated thyroid cancer in Sweden
(2006-01-06)
Non-medullary differentiated thyroid cancer (DTC) is a rare disorder but, nevertheless, among the most common cancers in individuals below 40 years of age. DTC consists of papillary (PTC) and follicular (FTC) thyroid cancer. ...
Genetic and immunological control of human myasthenia gravis
(2005-09-23)
is in strong linkage with -318C/T and is more frequently present in MG patients with thymoma. MG patients carrying -318C showed significantly decreased expression of CTLA-4 mRNA in non-stimulated cells. In the present study, the relationship of the expression...
Clinical and epidemiological aspects of pelvic floor dysfunction
(2004-10-08)
randomly selected women, 30-79 years old, from the Swedish Population Register. Two hundred and eighty-two of these women underwent a gynaecological examination of the pelvic floor anatomy. Specificity and sensitivity in the survey were 66.5 and 94.2...
Tobacco smoking and vertical periodontal bone loss
(2005-05-18)
study populations, Swedish musicians and a Saudi Arabian population. All participants had a full set of intra-oral radiographs including 16 periapical and 4 bitewing projections that were assessed with regard to presence or absence of vertical defects...
Family history and breast cancer susceptibility : clinical and molecular studies
(2006-09-15)
Apart from gender, family history is the most important risk factor for breast cancer. In 5-10 % of the cases there is a family history pattern of an autosomal dominant disease and there is also a familial clustering of ...
Barrett's oesophagus and metaplasia at the oesophagogastric junction : an epidemiological approach
(2006-11-03)
indicated 10.7- and 3.3-fold risks, respectively, for BO (95% Cl 3.5-33.4 and 1.1-9.9 respectively) in the comparison with population controls. Body mass was unrelated to risk. In the cross-sectional analysis among endoscopy room patients, reflux symptoms...
Molecular characterization of the Ro52 autoantigen and its disease related epitopes
(2005-01-14)
The presence of high titers of autoantibodies in patient sera is characteristic for the autoimmune disorder Sjögren s syndrome. The major targets for these autoantibodies are three intracellular proteins Ro52, Ro60 and La. ...
Bone anchored hearing aids 'BAHAs' in children
(2006-05-26)
BACKGROUND: The technique for applying bone-anchored hearing aids (BAHAs) by the use of osseointegration is today widely established for both adults and children. The BAHA concept is suitable for patients with recurrent ...