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Stem cells : proliferation, differentiation, migration
(2005-12-23)
A stem cell is demanding and requires precise conditions to carry out its unique tasks. This includes proliferation as an undifferentiated stem cell, differentiation to more mature cell types, migration through tissue to ...
Mucosal immune responses in HIV-1 exposed uninfected individuals
(2006-10-20)
The development of HIV vaccines and immunotherapeutics remains hampered by our lack of understanding correlates of immune protection to infection and disease. The major (perhaps only) piece of evidence indicating that ...
Chemoattractants as causative agents, biomarkers and therapeutic targets in vascular pathology
(2006-09-22)
Atherosclerosis and restenosis are driven by chronic immune response in the vascular wall. This involves cell migration into and within the vessel wall, cell proliferation as well as accumulation of lipids in the vessel ...
Coreceptor usage and sensitivity to neutralization of HIV-1 and HIV-2
(2004-11-05)
The aim of this project was to study neutralization and coreceptor use in HIV-1 and HIV-2. The first step was to develop a simple and standardized assay for detection and quantification of HIV- 1 neutralizing activity in ...
Studies of high mobility group chromosomal protein 1 as a pro-inflammatory cytokine
(2005-05-27)
High mobility group box chromosomal protein 1 (HMGB 1) is a nuclear protein recently recognised as a pro-inflammatory cytokine with implications both in acute and in chronic inflammation. HMGB1 has been reported to act as ...
Women’s health after childbirth
(2006-11-17)
The overall aim of this thesis is to describe women's health after childbirth in a national Swedish sample by investigating the prevalence of a number of physical symptoms and self-rated health (SRH). The prevalence of ...
Cognitive rehabilitation in children with acquired brain injuries
(2005-07-29)
Deficits in attention, memory and executive functions are the most common cognitive dysfunctions after acquired brain injuries (ABI) and may have a major negative influence on academic and social adjustment. Neuropsychological ...
Physical activity in rheumatoid arthritis
(2006-04-28)
Physical activity confers health benefits in the general population and should also be applied to people with rheumatoid arthritis (RA). However, there is a need for more research in this area. The aim of this thesis was ...
Prevention of complications in pediatric cataract surgery
(2004-11-26)
This thesis was performed to find ways to lessen the complications to pediatric cataract surgery, which is an increasingly safe procedure, also in infants. However, there are some complications to the surgery, which threatens ...
Lung function in micro- and in hypergravity
(2005-05-06)
The lung is extremely susceptible to gravity, even during short-term changes of the gravity vector, because it is a mixture of air and elastic tissue components. Yet, there is limited knowledge of the effects of gravity ...