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Standardization and application of quantitative PCR methods in patients with hematological malignancies
(2004-10-29)
Using modem combination chemotherapy regimens, it has been possible to increase the rate of complete remission (CR) in acute lymphoblastic (ALL) and acute myeloid leukemia (AML). The major reason for treatment failure in ...
Bad breath : prevalence, periodontal disease, microflora and inflammatory markers
(2005-03-29)
)] and 841 woman [mean age = 35.7 years (±2.9 SD)] who participated in an epidemiological study of periodontal health that was started in 1985, 2.4 % were found to exhibit foetor ex ore and 1 % were diagnosed as having halitophobia. Subjects with both...
Genetic studies of follicular and mantle cell lymphoma
(2005-04-22)
Non-Hodgkin lymphoma is a malignancy derived from lymphoid tissues. In Sweden, non-Hodgkin lymphoma constituted 3% of all cancers recorded in 2003. Follicular and mantle cell lymphoma are the two types of non-Hodgkin ...
Mechanisms of rhythm generation in the lamprey locomotor network
(2004-09-15)
Animals propel themselves through space, swimming, walking or flying, by rhythmic oscillatory movements of their body and limbs. In vertebrates these movements are mainly generated by specialized neuronal circuits in the ...
Renal cell death in urinary tract infections : role of E. coli toxins
(2005-01-28)
Febrile urinary tract infections (UTI) are common bacterial illnesses in children. Several follow up studies have shown that 10-15 % of infants with pyelonephritis will develop permanent renal damage, i.e., renal scars, ...
Coronary artery bypass surgery without extracorporeal circulation
(2006-03-10)
Introduction: Coronary artery bypass surgery with extracorporeal circulation is associated with a systemic inflammatory response syndrome that contributes to morbidity and mortality. Aortic cross clamping and cardioplegic ...
Women’s health after childbirth
(2006-11-17)
The overall aim of this thesis is to describe women's health after childbirth in a national Swedish sample by investigating the prevalence of a number of physical symptoms and self-rated health (SRH). The prevalence of ...
Mediators of cervical ripening in preterm birth : experimental and clinical investigations
(2005-05-05)
Background: Preterm birth (PTB) is by far the leading worldwide cause of infant mortality and morbidity. Despite decades of research, the frequency of PTB has not decreased and the basic mechanisms initiating the onset of ...
Diabetes, physical activity and endometrial cancer
(2006-11-22)
Accumulating evidence suggests that hyperinsulinemia, in the context of insulin resistance, is associated with carcinogenesis. Physical activity is involved in the regulation of metabolic and hormonal pathways and is an ...
Antimicrobial peptides and proteins in innate immunity : emphasis on isolation, characterization and gene regulation
(2005-03-18)
Antimicrobial peptides are endogenous antibiotics and effector molecules
of Innate immunity. These peptides are mainly localised to epithelial
linings and circulating neutrophils. They kill microbes by disruption of
their ...