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The study of sensory cilia development in Caenorhabditis elegans
(2008-01-04)
Cilia and flagella are widespread eukaryotic subcellular components
that are conserved from green algae to mammals. In different organisms
they function in cell motility, movement of extracellular fluids and
sensory ...
The role of angiomotin in endothelial cell motility and cell-cell junction formation
(2005-08-26)
Clinical as well as pre-clinical data show that tumor growth can be restrained by inhibiting angiogenesis. We have been investigating the mechanism of action of angiostatin, an inhibitor of angiogenesis, in order to design ...
Development of a vaccine against strangles
(2005-09-16)
Strangles is an acute upper respiratory tract disease in the horse, which is characterized by purulent pharyngitis and lymphadenitis. It is caused by Streptococcus equi subsp. equi. The severe suffering and economical ...
Posterior capsule opacification and postoperative endophthalmitis following cataract surgery : predictive and protective factors
(2005-04-01)
Modem cataract surgery with implantation of an intraocular lens (IOL) is an increasingly safe and successful procedure, though complications still occur. This thesis addresses the most common complication, posterior capsule ...
Estrogen and liver X receptors in human disease
(2006-11-10)
pathophysiological conditions in which the NRs are involved. Four NRs, the estrogen receptors (ERs) α and β, and liver X receptors (LXRs) α and β, are studied in this thesis. The ERs have been implicated in several human diseases such as breast cancer, osteoporosis...
Differential RNA expression in benign and malignant adrenocortical tumours
(2005-11-21)
Adrenocortical cancer is a rare but very aggressive endocrine tumor, with a yearly incidence of 0.5 to 2 cases per million inhabitants, accounting for 0.2% of all cancer related deaths. This contrasts to the high prevalence ...
Aspects on the psychopharmacology of cholecystokinin
(2005-05-20)
This thesis includes studies of the effect of mild stress on brain cholecystokinin (CCK), anatomy of markers for CCK-ergic transmission in the brain and the systemic effect of CCK receptor stimulation in a clinical test ...
Humming, nitric oxide and paranasal sinus ventilation
(2006-04-21)
The paranasal sinuses are air-filled bony cavities surrounding the nose. They communicate with the nose via the sinus ostia through which fluid and gases pass in both directions. A proper ventilation is crucial for sinus ...
Influence of the microflora on gastrointestinal nitric oxide generation : studies in newborn infants and germ-free animals
(2006-05-11)
Interactions between intestinal bacteria and the host play an important role in physiological regulation of gut function and in development of various diseases. Nitric oxide (NO) exhibits a variety of biological actions ...
Molecular studies of complications in end stage renal disease : focus on expression and variations of candidate susceptibility genes
(2005-09-09)
End stage renal disease (ESRD) is a complex multifactorial disorder, where both environmental and genetic factors are contributing to the phenotype. The most common complications seen in ESRD patients are malnutrition, ...