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Catalytic mechanisms and evolution of leukotriene A4 hydrolyse
(2006-11-10)
of chemical mediators, which by different means control, maintain and resolve the process. One group of such mediators is the leukotrienes, among which LTB4 is found. LTB4 has several immunomodulating properties and mainly acts by recruiting leukocytes...
Viridans group streptococci septicaemia and endocarditis : molecular diagnostics, antibiotic susceptibility and cinical aspects
(2005-04-27)
was found in oral swabs from haematological patients where 25% of the VGS isolates were resistant to penicillin (MIC ≥ 4.0 μg/ml), which was higher that we had expected. This is an important observation because the oral cavity has been described as a genetic...
The post-polio syndrome : studies of immunology and immunomodulatory intervention
(2005-09-02)
patients. The PPS patients displayed greater numbers of CSF cells expressing mRNA for TNF-alpha (p<0.02), IFN-gamma (p< 0.02), IL-4 (p<0.001) and IL-10 (p<0.05), compared to eight controls with other neurological disorders (OND). The level of increase...
Calcium dynamics and vesicle-release proteins in a prion-infected neuronal cell line
(2005-03-25)
The prion particle, PrPSc, is an infectious, misfolded form of the cellular prion protein, PrPC that is expressed at high levels in the central nervous system. Prions cause neurodegenerative diseases with clinical signs ...
Genetic and immunological control of human myasthenia gravis
(2005-09-23)
is in strong linkage with -318C/T and is more frequently present in MG patients with thymoma. MG patients carrying -318C showed significantly decreased expression of CTLA-4 mRNA in non-stimulated cells. In the present study, the relationship of the expression...
Pathogenesis of type 2 diabetes with emphasis on the mechanism of insulin resistance
(2006-09-15)
Type 2 diabetes is characterized by chronic hyperglycemia and develops slowly through stages of early impairments of glucose metabolism. The disease is often associated with obesity, physical inactivity, decreased insulin ...
Tobacco smoking and vertical periodontal bone loss
(2005-05-18)
study populations, Swedish musicians and a Saudi Arabian population. All participants had a full set of intra-oral radiographs including 16 periapical and 4 bitewing projections that were assessed with regard to presence or absence of vertical defects...
On neck load among helicopter pilots : effects of head worn equipment, whole body vibration and neck position
(2005-09-13)
increased by about 0.5-1 % MVE as a function of vibration at frequencies around 4-5 Hz, with the higher levels when the neck was flexed. Muscle activity was also affected by vibration magnitude, where lower-neck-muscle and trapezius activity increased...
DNA lesions and carcinogenicity from the urban air pollutants 2- and 3-nitrobenzanthrone
(2006-11-10)
In the early 1990's, Japanese doctors in urban areas discovered an increasing incidence of lung cancer among women, which was not attributed to a change in diet or smoking. This led to a growing investigation of urban air, ...
Effects of mifepristone on the human endometrium and the fallopian tube during the luteal phase
(2005-05-19)
(the expected time for endometrial receptivity and implantation) and the fallopian tube on day LH+4 to LH+6 (approximately the time when the embryo is still in the fallopian tube). Immunohistochemistry, RT-PCR and Western blot were used for analysis...