Search
Now showing items 1-10 of 109
Fusion activation in murine leukemia virus
(2006-04-21)
This thesis describes the fusion activation in Murine leukaemia virus (MLV). During entry of retroviruses into uninfected cells, the viral and cellular membranes fuse. The fusion process is mediated by the viral envelope ...
Multimethodological imaging studies of pathophysiological mechanisms in human epilepsy
(2006-08-11)
Although the pathophysiological mechanisms of human epilepsy are extensively investigated, many questions remain unanswered. One is whether idiopathic generalized epilepsies (IGE) have anatomical substrates. Another is if ...
Application of two fluorescence methods for detection and quantification of smooth surface carious lesions
(2006-05-17)
Early diagnosis of carious lesions is a key factor in prevention and management of dental caries. With non-invasive, quantitative diagnostic methods it should be possible to detect lesions at an initial stage and subsequently ...
The insulin-like growth factor system : effects of circulating proteases
(2005-08-18)
) increases serum IGFBP-3 proteolysis or IGFBP-1 in healthy adults. This was investigated since IL-6 is elevated in several inflammatory diseases associated with increased MF13P-3 proteolysis. We found that a 3-hour IL-6 infusion did not increase IGFBP-3...
Coronary artery bypass surgery without extracorporeal circulation
(2006-03-10)
Introduction: Coronary artery bypass surgery with extracorporeal circulation is associated with a systemic inflammatory response syndrome that contributes to morbidity and mortality. Aortic cross clamping and cardioplegic ...
Molecular genetic studies of psoriasis susceptibility in 6p21.3
(2005-02-18)
, the genetic contribution to the disease is strong. Several loci have been identified and among these, psoriasis susceptibility 1 (PSORS1) in chromosome region 6p21.3 is consistently described in populations of different ethnic background. A major factor...
Pituitary autoantibodies in endocrine disorders
(2005-09-30)
by immunoblotting. Reactivity to a M, 49 000 pituitary autoantigen was significantly more frequent in patients with idiopathic pituitary hormone deficiency (6/21 (28%) p< 0.05) as well as their relatives (10/35 (28%) p<0.02) compared to control subjects (3/44 (6...
Antimicrobial peptides and proteins in innate immunity : emphasis on isolation, characterization and gene regulation
(2005-03-18)
Antimicrobial peptides are endogenous antibiotics and effector molecules
of Innate immunity. These peptides are mainly localised to epithelial
linings and circulating neutrophils. They kill microbes by disruption of
their ...
Immersion and recreational boating-related injuries in Alaska
(2005-11-04)
Background: Cold water is an ever-present hazard in Alaska, and when water-related injuries occur, they often take place in remote environments, where the nearest trained emergency response teams are several hours away. ...
Novel methods for the identification of cellular S-glutathionylated proteins and sites of glutathionedependent modification using affinity chromatography and proteomic analyses
(2005-02-21)
Reactive oxygen species (ROS) are formed during normal respiration in the mitochondria through electron leakage to oxygen. During normal metabolism, several enzymes and low-molecular weight antioxidants work towards ...