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Novel signaling pathways : induced by bacterial toxins in eukaryotic cells
(2005-09-23)
Inflammation is the process by which the host counteracts microbes that are constantly exposing the human body. These microbes rarely cause disease, due to the effective defense mechanisms of the host immune system. Although ...
Chemoattractants as causative agents, biomarkers and therapeutic targets in vascular pathology
(2006-09-22)
Atherosclerosis and restenosis are driven by chronic immune response in the vascular wall. This involves cell migration into and within the vessel wall, cell proliferation as well as accumulation of lipids in the vessel ...
An epidemiological study og drug-induced acute pancreatitis utilizing a Swedish case-control network
(2006-01-06)
population. Information was obtained from medical records and through telephone interviews.
Overall, there were 2,453 potential patients and 2,245 potential controls among whom 779 and 2,128, respectively, were eligible for inclusion. 462 patients and 1...
The role of red blood cells in inflammation and remodeling
(2004-08-27)
Besides being carriers of oxygen and carbon dioxide, red blood cells (RBCs) also have a scavenger function, binding inflammatory mediators to surface receptors. Animal and experimental models have suggested a role for RBCs ...
The role of the endothelin system in experimental acute lung injury : with special reference to the formation of extra-vascular lung water
(2006-05-12)
Acute lung injury is a major clinical challenge in the intensive care unit. Sepsis is the most frequent underlying cause of this pulmonary syndrome, which contains inflammation-induced diffuse alveolar damage and early ...
Off-label drug treatment and related problems in children : a register-based investigation
(2006-04-21)
Introduction: There is a lack of pediatric documentation concerning efficacy and safety of many drugs, which may contribute to off-label drug treatment and increase the risk for adverse drug reactions (ADRs).
Aims: ...
Genes of the serotonergic system and susceptibility to psychiatric disorders : a gene-based haplotype approach
(2006-05-24)
Psychiatric disorders are complex, non-mendelian disorders. Complex disorders are ultimately determined by a number of genetic and environmental factors, and the effect of each factor may be obscured or confounded by others. ...
Influence of the microflora on gastrointestinal nitric oxide generation : studies in newborn infants and germ-free animals
(2006-05-11)
Interactions between intestinal bacteria and the host play an important role in physiological regulation of gut function and in development of various diseases. Nitric oxide (NO) exhibits a variety of biological actions ...
Risk factors for haematological malignancies : immune-mediated diseases, body mass index and magnetic fields
(2006-11-03)
Haematological malignancies constitute approximately 7% of all cancer cases in Sweden, and leukaemia is in fact the most common malignancy among children. The few established risk factors, such as ionising radiation and ...
Diabetes, physical activity and endometrial cancer
(2006-11-22)
of total physical activity to the lowest one were 0.80 (95% CI 0.541.18); 0.87 (95% CI 0.59-1.28); 0.79 (95% CI 0.53-1.17) respectively. High leisure time inactivity (watching TV/sitting 5 hours or more a day) compared to low was associated with increased...