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Chemoattractants as causative agents, biomarkers and therapeutic targets in vascular pathology
(2006-09-22)
-PSOX, which mediates uptake of oxidized low-density lipoprotein (oxLDL) by cells. We detected abundant CXCL16/SR-PSOX and CXCR6 expression in atherosclerotic lesions from human subjects and apolipoprotein-Edeficient (ApoE-/-) mice. In monocytes, CXCL16/SR...
Synthesis of indole and oxindole derivates incorporating pyrrolidino, pyrrolo or imidazolo moieties
(2004-11-26)
-chloroacrylonitrile yielded, after expulsion of HCN by refluxing in ethanol, 1-benzyl-4,5,6,7-tetrahydroindole. Formylation and benzylimine formation followed by treatment with TosMIC furnished the desired 2-imidazolyltetrahydroindole....
Children with high and intermediate imperforate anus : aspects of care and psychosocial effects of the malformation
(2005-10-21)
The overall aim of this thesis was to investigate the experiences of
children with high and intermediate imperforate anus and of their
parents; how they have experienced care and treatment and what
consequences the ...
Diabetes, physical activity and endometrial cancer
(2006-11-22)
Accumulating evidence suggests that hyperinsulinemia, in the context of insulin resistance, is associated with carcinogenesis. Physical activity is involved in the regulation of metabolic and hormonal pathways and is an ...
Viridans group streptococci septicaemia and endocarditis : molecular diagnostics, antibiotic susceptibility and cinical aspects
(2005-04-27)
Viridans group streptococci (VGS) are inhabitants in the oral cavity and in the gastrointestinal tract. They cause severe infections, they are responsible for up to 39 % of the cases of septicaemia in neutropenic patients ...
Study of serotonin, innervation and sensory neuropeptides in allergic contact dermatitis
(2005-08-17)
In a murine model of contact allergy, 24 h after challenge with antigen, increased axonal growth using an antibody to growth-associated protein-43 (GAP-43) was seen in the epidermis and dermis of eczematous skin. Protein ...
On the genetic variation of interleukin-6 in health and coronary heart disease
(2005-03-18)
of IL-6 in healthy subjects and patients with CHD are largely unknown and remain to be defined. Thrombosis underlies most of the acute manifestations of CHD including myocardial infarction. The causes of thrombosis are not fully clear, but an important...
Long-term neurodevelopmental outcome after moderate neonatal encephalopathy and after post-term birth : two population-based studies
(2006-03-17)
Long-term neurodevelopmental outcome in two population-based groups of children with different perinatal events was studied: A) Children born at term with moderate neonatal encephalopathy (NE) and B) children born post-term ...
Inflammatory status in adolescents : the impact of health determinants such as overweight and fitness
(2006-03-07)
Overweight prevalences are rising among youth and the prevention of associated chronic diseases is priority concern in public health. Inflammatory processes are involved in the pathogenesis of cardiovascular diseases and ...
Non-conventional risk and prognostic factors in coronary heart disease : studies on heart rate variability, alcohol consumption, inflammation and depression
(2005-04-01)
not relate to any of the HRV parameters (paper I). Concentration of IL-6 showed an inverse relation to HRV even after adjustment for potential confounding factors (paper II). HRV parameters predicted all-cause and cardiovascular mortality in a 9-year follow...