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The impact of estrogens on leukocyte function in remodeling of extracellular matrix
(2005-11-23)
ERalpha agonist PPT (4,4',4"-(4-Propyl-[lII]-pyrazole-1,3,5 -triyl)trisphenol) and the selective ERbeta agonist DPN (2,3bis(4hydroxyphenyl)-proprionitrile) on gene expression profiles in a rat animal model. This study reports the identification of genes...
Unstimulated human whole saliva flow rate in relation to hyposalivation and dental caries
(2005-04-08)
Introduction: Salivary secretion is influenced by a large number of factors, including the circadian rhythm, making the detection of reduced salivary flow (hyposalivation) difficult. This is important since severely reduced ...
Children's diarrhea in Hanoi, Vietnam : importance of enteric pathogens
(2005-02-18)
Diarrhea is one of the leading causes of illnesses and death among
children in developing countries, where an estimated 1.3 billion episodes
and 4 to 10 million deaths occur each year in children less than 5 years
of ...
The post-polio syndrome : studies of immunology and immunomodulatory intervention
(2005-09-02)
baseline in patients receiving IVIG, while the placebo group displayed a 5.8 % decrease ( p=0.029). Five of eight subscales of the SF 36 improved significantly over baseline in the IVIG group, but none in the placebo group. Two subscales, vitality...
Synthesis of indole and oxindole derivates incorporating pyrrolidino, pyrrolo or imidazolo moieties
(2004-11-26)
-chloroacrylonitrile yielded, after expulsion of HCN by refluxing in ethanol, 1-benzyl-4,5,6,7-tetrahydroindole. Formylation and benzylimine formation followed by treatment with TosMIC furnished the desired 2-imidazolyltetrahydroindole....
Platelets and eosinophils in lung tissue remodelling
(2006-08-25)
Tissue injury and inflammation followed by effective repair restores normal function, but defective repair with associated tissue remodelling and fibrosis can lead to loss of organ function. Thus, interactions between ...
The role of incretin peptides and ghrelin in upper gut motility and metabolic control
(2006-11-24)
Metabolic control is essential for the individual and is strictly regulated via a wide range of factors. One important mechanism in maintaining an adequate blood sugar level is the regulation of insulin release and gastric ...
Biological activities of novel platelet-derived growth factors, PDGF-C and PDGF-D
(2004-09-17)
Platelet-derived growth factors (PDGFs) belong to the PDGF/VEGF (vascular endothelial growth factor) family of growth factors. Members of this family share a common structural feature, a conserved PDGF/VEGF homology domain, ...
Molecular mechanisms regulating exocytosis : studies of insulin secretion and neurotransmitter release
(2005-02-11)
expressed in neurons. Cdk5 was identified in pancreatic ?-cells where it functions as a positive regulator of insulin secretion. Although ?-cells expressed both of the identified Cdk5 regulatory subunits, only Cdk5, activated by p39, enhanced insulin...
Diabetes, physical activity and endometrial cancer
(2006-11-22)
of total physical activity to the lowest one were 0.80 (95% CI 0.541.18); 0.87 (95% CI 0.59-1.28); 0.79 (95% CI 0.53-1.17) respectively. High leisure time inactivity (watching TV/sitting 5 hours or more a day) compared to low was associated with increased...