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Chemoattractants as causative agents, biomarkers and therapeutic targets in vascular pathology
(2006-09-22)
(SNP) in the CCL11 gene and related the presence of the former to the plasma CCL11 concentrations, measured by ELISA. There were no differences in CCL1 genotype frequencies between patients and controls. Patient G/G carriers had higher circulating CCL11...
Methods and detection of endogenous peptides in the CNS and GI tract
(2006-11-15)
Endogenous peptides, such as enkephalins, endorphins and orexins modulate a variety of biological processes; these peptides are found in the central nervous system and periphery, including the gastrointestinal tract. One ...
Structural and functional studies of microsomal glutathione transferase 1
(2005-05-13)
The microsomal glutathione transferase 1 (MGST1) is present in high amounts in the endoplasmic reticulum (ER) as an integral homo-trimeric membrane protein with a molecular weight of 51.9 kDa. MGST1 possess glutathione transferase and peroxidase...
The influence of psychosocial stress, socioeconomic differences and coffee consumption in the etiology of type 2 diabetes
(2004-12-24)
diabetes in women (RR=2.2, CI:1.04.8 and RR=3.7, CI:1.2-11.2, respectively). The underlying mechanisms may involve psychosocial stress inducing insulin resistance via psychoendocrine pathways. However, high demands at work did not influence...
The role of incretin peptides and ghrelin in upper gut motility and metabolic control
(2006-11-24)
and GLP-1 on gastric emptying, metabolic control and appetite after intake of a mixed meal in man. In addition, I (3) studied the effects of ghrelin on smooth muscle contractility in rat and (4) its effect on gastric emptying in humans after intake of a...
Synthesis of indole and oxindole derivates incorporating pyrrolidino, pyrrolo or imidazolo moieties
(2004-11-26)
-component reactions between isatin, alpha-amino acid derivatives, and suitable dipolarophiles. Condensation between isatin and an alpha-amino acid yielded a cyclic intermediate, an oxazolidinone, which decarboxylate to give a 1,3-dipolar species, an azomethine ylide...
Learning to be a physiotherapist
(2006-05-12)
Few studies have explored student experience of learning in physiotherapy and none has explored student experience throughout an education programme from a student perspective. The traditional role of physiotherapists as ...
Molecular studies of complications in end stage renal disease : focus on expression and variations of candidate susceptibility genes
(2005-09-09)
the expression of ApM1 in fat tissue from patients with a high prevalence of MIA complications, patients who had few complications and healthy matched controls. We found that the ApM1 gene expression was markedly decreased in ESRD patients as compared to controls...
Dietary and genetic factors in the etiology of prostate cancer
(2006-05-19)
The etiology of prostate cancer is poorly understood. However, genetic factors may be more important than for many other malignancies. In addition, several studies suggest that dietary factors axe of etiologic importance. ...
Bibliometrics as a research assessment tool : impact beyond the impact factor
(2006-10-27)
Introduction: While bibliometrics is frequently used as a tool for research assessment and is thought of as objective, quantitative and unobtrusive, the usability of bibliometric indicators has seldom been properly assessed ...