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Synovial metabolism after knee joint arthroscopy : a microdialysis study
(2006-03-03)
of adrenaline on local metabolism and blood flow. In the fourth and last study we also monitored the above compounds and PGE2 and the relation to subjective pain.
In all studies we performed a standard arthroscopy in general anaesthesia except in study II...
Drug utilization 90% : using aggregate drug statistics for the quality assessment of prescribing
(2004-08-27)
, primary
health care (PHC) centres and clinics; (2) develop a method for the
quality assessment of drug prescribing based on routinely available
aggregate drug statistics; (3) analyse the strengths and limitations of
the proposed method when it is applied...
Synthesis of indole and oxindole derivates incorporating pyrrolidino, pyrrolo or imidazolo moieties
(2004-11-26)
The focus of this thesis is on the synthesis of oxindole- and indole-derivatives incorporating pyrrolidins, pyrroles or imidazoles moieties.
Pyrrolidino-2-spiro-3'-oxindole derivatives have been prepared in high ...
Capsulotomy in anxiety disorders
(2006-05-26)
. Mean Y-BOCS was 34 preoperatively and dropped to 18 at long-term follow-up (p<0.0001). Only 2 patients achieved remission from OCD without substantial side effects. Several neurosurgical complications related to radiosurgery were reported. Two patients...
HIV-2 genetic evolution and viral dynamics
(2006-05-03)
HIV-2 is less pathogenic and less transmissible compared to HIV-1. This is believed to be due to the lower viral load that is seen in HIV-2 infected patients. However, why this lower viral load is seen is not known. In this thesis we have...
Regulation of carbohydrate metabolism in skeletal muscle during and after contraction
(2006-11-03)
during exercise will lead to new strategies for treating or preventing increasingly prevalent diseases like type 2 diabetes. The aim of this thesis was to study the regulation of carbohydrate metabolism in skeletal muscle during and after contraction...
Diabetes, physical activity and endometrial cancer
(2006-11-22)
cancer, we identified 16 studies (3 cohort and 13 case-control studies), and found that diabetes was statistically significantly associated with an increased risk of endometrial cancer incidence, (summary RR = 2.10 95% CI= 1.75-2.53). Analysis of 2...
Apnea and infection in neonates : mediatory role of interleukin-1Beta and prostaglandin E2
(2006-11-10)
The breathing pattern of infants, particularly preterm infants, is often irregular or periodic and is frequently interrupted by apnea. The latter represents a major concern in haematology, yet much remains unknown about ...
Pathogenesis of type 2 diabetes with emphasis on the mechanism of insulin resistance
(2006-09-15)
Type 2 diabetes is characterized by chronic hyperglycemia and develops slowly through stages of early impairments of glucose metabolism. The disease is often associated with obesity, physical inactivity, decreased insulin sensitivity and impaired...
Risk factors for haematological malignancies : immune-mediated diseases, body mass index and magnetic fields
(2006-11-03)
Haematological malignancies constitute approximately 7% of all cancer cases in Sweden, and leukaemia is in fact the most common malignancy among children. The few established risk factors, such as ionising radiation and ...