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2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) disrupts vitamin A homeostasis in rodents : quantitative and mechanistic studies to support risk assessment
(2005-11-25)
(1) to clarify the species and
strain sensitivity of TCDDinduced retinoid disruption and (2) to identify
cellular targets of TCDD-induced retinoid disruption.
Altered hepatic vitamin A gain was a sensitive measure of TCDD exposure
in guinea pigs...
Functional studies on the interaction of immunoglobulins with HIV-2 envelope
(2005-09-16)
Infection with HIV-2 has a much more limited geographic distribution than HIV-1, being less readily transmitted and is generally less pathogenic. The role of immunoglobulins in defence against pathogens in different body compartments is known, where...
Learning to be a physiotherapist
(2006-05-12)
Few studies have explored student experience of learning in physiotherapy and none has explored student experience throughout an education programme from a student perspective. The traditional role of physiotherapists as ...
Ethyl glucuronide : a new biochemical marker for acute alcohol intake : studies on possible causes for false-negative or false-positive results
(2006-02-17)
and dependence in hospital settings, work place settings, traffic medicine and in forensic toxicology examinations. The alcohol biomarkers can be distinguished into two main classes: 1) tests that are sensitive enough to detect a single intake of alcohol...
Dynamics of the HIV-2-specific immunoglobulin A(IgA) response
(2005-04-01)
that serum IgA in HIV-2 infected individuals had the capacity to neutralize HIV-2. Additionally, a strong serum IgA binding activity against a peptide (aa 644-658, MYELQKLNSWDVFGN) in the region of the central part of transmembrane envelope of HIV-2 (gp36...
Cytokines in the nervous system with emphasis on interleukin-1 receptor-mediated activity
(2005-03-11)
Interleukin-1 (IL-1) is one of the most important pro-inflammatory cytokines and plays a pivotal role in the neuroinflammation associated with certain forms of neurodegeneration, such as epilepsy, cerebral ischemia, trauma, and Alzheimer's disease...
Pituitary autoantibodies in endocrine disorders
(2005-09-30)
autoantigen in APS 1....
Modulation of the HPA axis alters the sensitivity of the cochlea to acoustic trauma
(2006-10-27)
PDTC was use to confirm the role of NFκB in the cochlea. Pretreatment of PDTC caused an elevation of auditory thresholds and lowered nuclear translocation of NFκB in the SGNs. Steroid receptor co activator 1 (SRC-1), a GR co-regulatory protein also...
Barrett's oesophagus and metaplasia at the oesophagogastric junction : an epidemiological approach
(2006-11-03)
indicated 10.7- and 3.3-fold risks, respectively, for BO (95% Cl 3.5-33.4 and 1.1-9.9 respectively) in the comparison with population controls. Body mass was unrelated to risk. In the cross-sectional analysis among endoscopy room patients, reflux symptoms...
Development of nuclear medicine methods for gastric and small bowel motility : effects of GLP-1 on gastric emptying
(2005-05-20)
The diagnosis of functional disorders of the gastrointestinal (GI) tract
requires techniques being both sufficiently sensitive to detect
disturbances of the normal physiology and low-invasive enough not to
interfere ...