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Now showing items 1-10 of 116
Telephone support for smoking cessation : the Swedish example
(2005-11-11)
. Study I comprised 496 and 629 smokers receiving a reactive and a proactive treatment respectively. Studies II, III and IV comprised all 1131 smokers who had signed up for smoking cessation treatment from February 2000 to November 2001. Of those, 741...
Cigarette smoking and silica exposure as determinants for the development of rheumatoid arthritis
(2004-10-21)
Rheumatoid arthritis (RA) is an autoimmune, inflammatory disease with obscure etiology. This thesis is based on the hypothesis, that there is a link between respiratory exposures and the development of RA. Cigarette smoking ...
Psychosocial risk factors in women with coronary heart disease : stress, social support and a behavioral intervention
(2005-09-16)
to survey psychosocial and physiological risk factors for CHD in women. Participants were 292 women <65 years (mean age 55±8 yrs) recruited while hospitalized, for acute myocardial infarction (AMI) or unstable angina pectoris from all hospitals in Stockholm...
Expression of cathelicidin antimicrobial peptides in man and rat
(2004-11-26)
Endogenous antimicrobial peptides are effectors of innate immunity. They kill microorganisms by disrupting their cell membranes, but are also believed to have signaling functions in the immune system. They are present in ...
Penicillin-resistant pneumococci in Sweden : epidemiology and public health response
(2005-12-30)
Since 1996, all identified cases of pneumococci with a MIC for penicillin G > 0.5 mg/L (penicillin resistant pneumococci: PRP) have been registered according to the Swedish Communicable Disease Act. In the same year, an ...
Mammographic breast density and postmenopausal hormone therapy
(2005-11-25)
Breast cancer is the most frequent malignancy among women in the western world. More than one million women are estimated to be diagnosed with the disease every year. The breast is a target organ for sex steroids and ...
The impact of social security compensation inequality on earnings distribution due to sickness and disability
(2005-08-26)
One of the main purposes of social security systems is to compensate for loss of earnings during periods of sickness and disability. Of interest is therefore the extent to which such compensation reduces earnings inequality. ...
Alterations in activity and specificity of intracellular proteolysis in disease pathogenesis
(2005-05-17)
The ubiquitin-proteasome pathway (UPP) plays a fundamental role in many basic cellular processes. Virtually all events in cellular physiology include control by the ubiquitin-proteasome pathway. Ubiquitinated substrates ...
Platelets and eosinophils in lung tissue remodelling
(2006-08-25)
Tissue injury and inflammation followed by effective repair restores normal function, but defective repair with associated tissue remodelling and fibrosis can lead to loss of organ function. Thus, interactions between ...
Characterisation of CD8 T cells in mucosa associated lymphoid tissue : implications for immune control of HIV-1 infection
(2006-02-24)
The role of CD8 T cells has been implicated in the partial immune control of HIV-1 infection. Ultimately these cells fail to control the infection and immune deficiency ensues in the absence of antiretroviral therapy. A primary focus of this thesis...