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Cataract from ultraviolet radiation in the mouse
(2005-11-25)
linkage is observed among several mammals, the human and the laboratory mouse genomes are by far the most extensively characterized and compared. This study introduces the C57BL/6 mouse as a model for UVR cataractogenesis and provides basic information...
Chemoattractants as causative agents, biomarkers and therapeutic targets in vascular pathology
(2006-09-22)
-PSOX, which mediates uptake of oxidized low-density lipoprotein (oxLDL) by cells. We detected abundant CXCL16/SR-PSOX and CXCR6 expression in atherosclerotic lesions from human subjects and apolipoprotein-Edeficient (ApoE-/-) mice. In monocytes, CXCL16/SR...
Investigations or perimetry and gaze-stability in healthy and deceased retina
(2005-11-30)
Our visual world is composed of images of colours, textures, edges and contrasts. In addition, these images may be moving or flickering. The goal of visual testing is to quantify these functions. Traditionally we have ...
Somato-psycho-social aspects of recovery after traffic injuries
(2006-10-27)
the patient's background and the injuries were collected and the patients were asked to assess their functional health status during the week that had preceded the accident using the SF-36. The patients were followed up at 1 month and at 6 months by means of a...
Drug utilization 90% : using aggregate drug statistics for the quality assessment of prescribing
(2004-08-27)
Introduction: There is room for improvement in prescribing. Although a
range of indicators have been developed to assess the quality of
prescribing, none of them focus on all drugs and there is a gap between
what is ...
Health-related quality of life, treatment satisfaction and clinical aspects of patients with primary antibody deficiency receiving subcutaneous IgG self-infusions at home
(2006-10-20)
Patients with primary antibody deficiencies (PAD) are unable to produce sufficient amounts of antibodies and are therefore susceptible to severe bacterial infections. The standard therapy has been intravenous infusions of ...
Infectious endocarditis, aspects on pathogenesis, diagnosis and prognosis
(2005-04-22)
The incidence of infectious endocarditis (IE) is estimated to 5.9/100.000 inhabitants and year. In recent years there has been an improvement in prognosis mainly due to more sensitive echocardiographic methods and surgery ...
Alterations in activity and specificity of intracellular proteolysis in disease pathogenesis
(2005-05-17)
The ubiquitin-proteasome pathway (UPP) plays a fundamental role in many basic cellular processes. Virtually all events in cellular physiology include control by the ubiquitin-proteasome pathway. Ubiquitinated substrates ...
Matrix metalloproteases and cell motility in malignant mesothelioma
(2004-10-29)
in malignant mesothelioma cells. All investigated mesothelioma cell lines expressed mRNA for MMP-1, MMP-2, MMP-3, MMP-9 and 6/8 cell lines expressed MMP-7, 3/8 cell lines expressed MMP-10. MMP-11 was not detected in any of mesothelioma cell lines tested. MMP-2...
Neuromodulation within a spinal locomotor network : role of metabotropic glutamate receptor subtypes
(2004-10-29)
The metabotropic glutamate receptors, mGluRs, are G-protein coupled receptors. They consist of eight cloned subtypes, which are divided into three groups depending on the amino acid sequence similarity, pharmacology and ...