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Design and synthesis of steroid mimetic libraries using solid phase techniques
(2004-09-10)
This thesis deals with the design and synthesis of biologically active ligands for nuclear hormone receptors using combinatorial techniques.
In the first part, a 5,6,6a,7,8,9,10,10a-octahydrobenzo[f]quinolin-3(4H)-one tricyclic core structure...
Myasthenia gravis : clinical aspects and possible involvement of prolactin
(2006-09-15)
controls. The levels of plasma PRL were raised in 101 women with MG, but not in 91 men. There was an association between high prolactin levels and high levels of autoantibodies against the AChR. There was no association between PRL levels and thymic...
Chemoattractants as causative agents, biomarkers and therapeutic targets in vascular pathology
(2006-09-22)
Atherosclerosis and restenosis are driven by chronic immune response in the vascular wall. This involves cell migration into and within the vessel wall, cell proliferation as well as accumulation of lipids in the vessel ...
The natural history of HIV-1 infection and preparations for HIV vaccine trials in Tanzania
(2006-09-08)
of the CD4+ T-lymphocyte counts and percentages among HIV-1 seroprevalents was found to be -21.5 cells/μ1 and -1.3% and among the HIV-1 seroincidents was -22.0 cells/μ1 and -1.5% respectively. The mean duration to a CD4' T lymphocyte level corresponding...
Urinary leakage and physical activity in young women
(2005-11-18)
and women with LBP the lowest. Before pregnancy, primiparous women reported 39% UL and 2% Ul, and one year postpartum 49% UL and 6% Ul. During trampolining, the ex-trampolinists reported 68% UL and 48% UI and 5-10 years afterwards 5 1% UL and 12% Ul...
Kvinnohälsa i perspektiv : studier med barnmorskor och läkare samt med kvinnor som vårdbrukare : exempel från cervixcancerscreening och obstetrisk vård av omskurna kvinnor
(2005-05-06)
In this thesis two areas of women's health are examined from different
stakeholder perspectives. The areas are cervical cancer screening (CCS;
articles I, III, V) and obstetrical care of circumcised/infibulated ...
Nitric oxide and evaluation of different treatments in experimental colitis and inflammatory bowel disease
(2006-11-10)
Inflammatory bowel disease (IBD), including ulcerative colitis (UC) and Crohn's disease (CD), is a chronic inflammatory disorder of unknown etiology of the gastrointestinal tract. Central features of IBD are increased ...
Neuromodulation within a spinal locomotor network : role of metabotropic glutamate receptor subtypes
(2004-10-29)
The metabotropic glutamate receptors, mGluRs, are G-protein coupled receptors. They consist of eight cloned subtypes, which are divided into three groups depending on the amino acid sequence similarity, pharmacology and ...
Local and systemic inflammatory mediators and their relation to pressure-pain threshold and pain of the temporomandibular joint
(2006-11-17)
condyle with a hand-held electronic pressure algometer (Somedic Production AB, Sollentuna, Sweden). TMJ pressure-pain threshold is systemically modulated and not modulated by the investigated inflammatory mediators (5-HT, TNFα, IL-1sRII) in the TMJ...
Learning to be a physiotherapist
(2006-05-12)
Few studies have explored student experience of learning in physiotherapy and none has explored student experience throughout an education programme from a student perspective. The traditional role of physiotherapists as ...