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Acute pain in pedatric patients : aspects of pain management and pain assessment
(2004-11-18)
in this thesis.
In order to evaluate efficacy and complications related to epidural analgesia (EDA) for postoperative pain, data from 518 epidural infusions in 476 children were analyzed retrospectively (study I). Epidural infusion for postoperative pain may...
Molecular regulation of microsomal triglyceride transfer protein gene, MTP : functional genetic studies in relation to cardiovascular disease
(2004-11-26)
The microsomal triglyceride transfer protein, MTP, is expressed mainly in
the liver, intestine and in the heart. It is crucial for the assembly and
secretion of apob-containing lipoproteins, chylomicrons in the intestine
and ...
Alzheimer´s disease-related amyloid precursor protein and presenlin genes : normal function and pathophysiology
(2004-10-08)
Alzheimer's disease (AD) is characterised neuropathologically by the presence of plaques and tangles in the brain. AD can be sub-grouped into early onset (EOAD, age of onset <65 yrs) and late onset (LOAD) forms, as well ...
The insulin-like growth factor system : effects of circulating proteases
(2005-08-18)
) increases serum IGFBP-3 proteolysis or IGFBP-1 in healthy adults. This was investigated since IL-6 is elevated in several inflammatory diseases associated with increased MF13P-3 proteolysis. We found that a 3-hour IL-6 infusion did not increase IGFBP-3...
Peptic ulcer disease in an adult population : the Kalixanda study – a population-based endoscopic study
(2006-12-21)
Introduction: The pattern of symptoms and perception of disease among
patients seeking care does, due to health care seeking behaviour, most
probably not reflect the true health status in the general population.
Upper ...
Posterior capsule opacification and postoperative endophthalmitis following cataract surgery : predictive and protective factors
(2005-04-01)
Modem cataract surgery with implantation of an intraocular lens (IOL) is an increasingly safe and successful procedure, though complications still occur. This thesis addresses the most common complication, posterior capsule ...
Oral mucosal lesions, tobacco use and the long-term outcome in a Swedish population
(2006-11-10)
to oropharyngeal cancer, there was a statistically significantly higher incidence among those who were or had been snus users compared to those who had never used snus, based on 11 exposed cases (IRR 3.1, 95% CI 1.5-6.6). For mortality ever daily smoking...
The analgesic mechanisms of buprenorphine
(2006-01-13)
of buprenorphine varies significantly in four inbred strains of mice (DBA2, C3H, C56BL/6 and 129). Significant between-strain differences were also seen for the antinociceptive effect of systemic morphine. The ranking order of potency was largely similar between...
Gastroesophageal reflux disease in adults : the Kalixanda study : a population-based endoscopic study
(2006-12-21)
Gastroesophageal reflux disease (GERD) is a common burden on health care
resources in the Western world and deteriorates the health-related
quality of life of those affected, but its manifestations in the general
population ...
Hidden Markov models for remote protein homology detection
(2005-12-23)
Genome sequencing projects are advancing at a staggering pace and are daily producing large amounts of sequence data. However, the experimental characterization of the encoded genes and proteins is lagging far behind. ...