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Studies on vascular remodeling in acute coronary artery disease
(2005-08-26)
Atherosclerosis is an arterial disease, characterized by endothelial dysfunction, vascular inflammation, and lipid accumulation in the vessel wall. Unstable coronary syndroms may be initiated by rupture of the atherosclerotic ...
Diagnostic methods in helicobacter pylori infection : development, evaluation and application
(2006-11-30)
Aim: To develop, evaluate and apply diagnostic methods for H. pylori infection.
Materials and Methods: An in-house Urea Breath Test (UBT) was developed and evaluated in three different settings, using serology by ...
Arthritogenic and immunogenic properties of modified autoantigens
(2005-03-22)
Rheumatoid arthritis is a chronic inflammatory joint disorder with autoimmune features in which both genetic and environmental factors are potential contributors to the arthritogenic process. In this thesis work we aimed ...
Regulation of gene and protein expression : two model systems
(2005-11-25)
Genetic information is expressed by DNA transcription and mRNA translation. With few exceptions, every cell of an organism, or the human body, contains the same genetic information. Yet the structure and function of different ...
Diagnosis of infection with Toxoplasma gondii in pregnant women, neonates and immunocompromised patients
(2005-09-09)
Infection with Toxoplasma gondii poses unique diagnostic problems like long-term persistence of specific IgM-antibodies, which makes it difficult to use the presence of Toxoplasma-specific IgM-antibodies alone as a sign ...
Oral mucosal lesions, tobacco use and the long-term outcome in a Swedish population
(2006-11-10)
The overall objectives of this thesis were to study the natural history for Oral Lichen (OLL), Oral Leukoplakia (OL) and Snus Induced Lesions (SIL) and to correlate cancer and mortality among users and non-users of Swedish ...
Children's diarrhea in Hanoi, Vietnam : importance of enteric pathogens
(2005-02-18)
Diarrhea is one of the leading causes of illnesses and death among
children in developing countries, where an estimated 1.3 billion episodes
and 4 to 10 million deaths occur each year in children less than 5 years
of ...
Characterisation of CD8 T cells in mucosa associated lymphoid tissue : implications for immune control of HIV-1 infection
(2006-02-24)
The role of CD8 T cells has been implicated in the partial immune control of HIV-1 infection. Ultimately these cells fail to control the infection and immune deficiency ensues in the absence of antiretroviral therapy. A primary focus of this thesis...
Study of serotonin, innervation and sensory neuropeptides in allergic contact dermatitis
(2005-08-17)
, both 5HT2AR, being CD3, CD4 or CD8 positive cells, and serotonin transporter protein (SERT) positive cells, being CD1a, CD4, CD8 positive or CD56+ CD3- cells, were increased. 5-HT3R immunoreactivity was seen in the basal epidermis of the inflamed...
Genetic and environmental factors in the development of externalizing symptoms from childhood to adolescence
(2005-11-11)
Externalizing problems, such as hyperactivity, impulsivity, aggression, violation of legal or social norms, and delinquent behavior, tend to persist from childhood to adolescence. There are also high levels of comorbidity ...