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Adaptive responses during giardia-host interactions
(2005-01-28)
Giardia lamblia is a major cause of water-borne enteric disease. The parasite is a noninvasive, flagellated protozoan that inhabits the upper part of the small intestine of its vertebrate hosts. Differentiation is central ...
Study of serotonin, innervation and sensory neuropeptides in allergic contact dermatitis
(2005-08-17)
, both 5HT2AR, being CD3, CD4 or CD8 positive cells, and serotonin transporter protein (SERT) positive cells, being CD1a, CD4, CD8 positive or CD56+ CD3- cells, were increased. 5-HT3R immunoreactivity was seen in the basal epidermis of the inflamed...
Heart failure : aspects on treatment and prognosis
(2006-05-02)
tests, treatment and follow up. The main part of the thesis, papers II-V, describe results from the OPTIMAL study which included two hundred and eight patients aged ≥ 60 years, hospitalised with systolic heart failure, and followed for (mean) 3.3 years...
Muscle protein synthesis : effects of metabolic stress and feeding
(2005-04-29)
Surgical trauma and critical illness are pathophysiological conditions where the metabolic stress leads to an imbalance between protein synthesis and protein breakdown, resulting in a net loss of body proteins. A major ...
Cellular and molecular mechanisms in abdominal aortic aneurysm growth and rapture
(2005-11-11)
, in contrast to normal aorta, were absent in the intimal layer of AAAs, and that MCs associate with medial and adventitial neovessels. Furthermore, MCs reside partly in the same areas with macrophages, CD3 positive T-cells and neutrophils. Cathepsin G...
Apoptosis in the myelodysplastic syndromes : protective effect of G-CSF
(2005-09-23)
Increased apoptosis of hematopoietic progenitor cells is a hallmark for
the myelodysplastic syndromes (MDS), and one of the main reasons for the
ineffective hematopoiesis and subsequent cytopenia characteristic for ...
Children with high and intermediate imperforate anus : aspects of care and psychosocial effects of the malformation
(2005-10-21)
The overall aim of this thesis was to investigate the experiences of
children with high and intermediate imperforate anus and of their
parents; how they have experienced care and treatment and what
consequences the ...
Carcinogenic polycyclic aromatic hydrocarbons : theoretical, molecular, in vitro and cellular characterization of biotransformation and DNA damage
(2005-05-13)
Polycyclic aromatic hydrocarbons (PAHs) are widespread mutagenic and
carcinogenic environmental pollutants, which require metabolic activation
to electrophilic intermediates and subsequent covalent binding to
critical ...
Human periodontal mechanoreceptors : functional properties and role in jaw motor control
(2005-04-29)
Periodontal mechanoreceptors signal information about tooth loads to the central nervous system and are considered to be important for the control of oral motor behaviors, like biting and chewing. Surprisingly, very little ...
Fat mass, adipokines and clinical complications of chronic kidney disease
(2006-05-26)
Patients with chronic kidney disease (CKD), irrespective of initial etiology, have a risk of cardiovascular morbidity (CVD) and mortality that is many-fold higher than that of a similar person without CKD. While traditional ...