Search
Now showing items 1-10 of 665
Individualized leukapheresis of hematopoietic cells for cellular therapies
(2005-11-24)
in peripheral blood and HSC collections is by their expression of the CD34-antigen. The optimal dose of HSC for transplantation is today considered to be >5x 106 CD34+ cells /kg bodyweight for prompt hematological recovery of all three lineages whereas a dose...
Chemoattractants as causative agents, biomarkers and therapeutic targets in vascular pathology
(2006-09-22)
Atherosclerosis and restenosis are driven by chronic immune response in the vascular wall. This involves cell migration into and within the vessel wall, cell proliferation as well as accumulation of lipids in the vessel ...
Synthesis of indoles, bisindoles and indolocarbazoles : high affinity aryl hydrocarbon receptor ligands
(2004-09-03)
,
the structure of which has also been confirmed by X-ray crystallography....
Syntheses of some tri- and tetracyclic heterocycles containing an indole moiety
(2004-11-19)
This thesis deals with the development of new synthetic methods leading to fused tri- and tetracyclic heterocycles, many of which have interesting biological activity such as antiviral and DNA intercalating properties.
The ...
Mild head injury : inhospital observation or computed tomography?
(2005-11-25)
Background: Patients with mild head injuries are treated every day in emergency
departments around the world. The rationale for any management strategy
is to identify with a high degree of safety at reasonable costs, ...
Therapeutic myocardial angiogenesis and its pharmacological modulation
(2005-09-30)
Angiogenesis is the formation of new blood vessels induced by the proliferation and migration of endothelial cells. Because angiogenesis is a complex process, therapeutic efficacy may be improved by overexpression of ...
Cataract from ultraviolet radiation in the mouse
(2005-11-25)
Cataract is defined as an opacification of the crystalline lens that results in visual impairment, Cataract is the number one cause of blindness in the world and there are currently no strategies to prevent it. Extraction ...
Cryo-electron tomography of individual protein molecules
(2005-08-29)
Averaging methods of determining structure, such as X-ray diffraction, do not preserve information about the flexibility of molecules. Cryo-electron tomography allows us to reconstruct individual hydrated objects. The method is limited to low...
Pulmonary tuberculosis in pre-trial detentions in St. Petersburg, Russia
(2006-01-06)
.
According to the WHO, a tuberculosis case is defined as a patient with bacteriologically confirmed tuberculosis or clinically diagnosed with TB. In the prison system in St. Petersburg the first and quick method for early TB diagnosis is the chest x...
Ideas of cure related to psychotherapy outcome : young adults in psychoanalytic psychotherapy
(2005-11-18)
Background: Ideas of cure within the psychoanalytical movement have mainly focused on 'insight' or 'interpersonal relationship'. Patients' ideas of curative factors during and after therapy have been studied previously, ...