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Chemoattractants as causative agents, biomarkers and therapeutic targets in vascular pathology
(2006-09-22)
-PSOX, which mediates uptake of oxidized low-density lipoprotein (oxLDL) by cells. We detected abundant CXCL16/SR-PSOX and CXCR6 expression in atherosclerotic lesions from human subjects and apolipoprotein-Edeficient (ApoE-/-) mice. In monocytes, CXCL16/SR...
Use of microbiomics to study human impacts on complex microbial communities
(2006-11-24)
The study of bacterial communities in nature is currently a challenge. The majority of bacteria in clinical and environmental samples have not yet been cultured and therefore we cannot fully understand their roles in nature ...
Computational exploration of human genome variation
(2004-09-03)
In studies of human genome variation, researchers attempt to identify the DNA sequence differences between our genomes that contribute substantially to variation that can be observed on a physical level (phenotype). Genetic ...
Somato-psycho-social aspects of recovery after traffic injuries
(2006-10-27)
the patient's background and the injuries were collected and the patients were asked to assess their functional health status during the week that had preceded the accident using the SF-36. The patients were followed up at 1 month and at 6 months by means of a...
Ideas of cure related to psychotherapy outcome : young adults in psychoanalytic psychotherapy
(2005-11-18)
Background: Ideas of cure within the psychoanalytical movement have mainly focused on 'insight' or 'interpersonal relationship'. Patients' ideas of curative factors during and after therapy have been studied previously, ...
Exercise and angiogenic growth factors in human skeletal muscle
(2005-05-20)
Long-term electrical stimulation and endurance exercise increase the amount of capillaries in skeletal muscle. VEGF-A is a well-characterized stimulatory angiogenic growth factor and has shown to play an important role in ...
Improving medical abortion : using mifepristone in combination with a prostaglandin analogue
(2005-09-16)
Background: Induced abortion is still a major health problem in the world and the most frequently performed intervention in Obstetrics and Gynaecology with an estimated total of 46 millions worldwide each year. Medical ...
On the genetic variation of interleukin-6 in health and coronary heart disease
(2005-03-18)
of IL-6 in healthy subjects and patients with CHD are largely unknown and remain to be defined. Thrombosis underlies most of the acute manifestations of CHD including myocardial infarction. The causes of thrombosis are not fully clear, but an important...
Biosynthesis of leukotriene B4 in hematological malignancies
(2005-05-27)
Leukotrienes (LT) are biologically active metabolites of the fatty acid
arachidonic acid (AA). After liberation of AA by phospholipase A 2 (PLA
2), this fatty acid can be converted to leukotrienes, lipoxins,
prostaglandins ...
Inflammation and matrix degrading proteases in coronary artery disease
(2006-05-26)
Coronary Artery Risk Factor (SCARF) study, a case-control study of 387 post-infarction patients and 387 healthy control persons, ii) 164 patients from the Thrombolysis and REOCclusion (TREOC) study, a longitudinal cohort study of patients with ST...