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Chemoattractants as causative agents, biomarkers and therapeutic targets in vascular pathology
(2006-09-22)
Atherosclerosis and restenosis are driven by chronic immune response in the vascular wall. This involves cell migration into and within the vessel wall, cell proliferation as well as accumulation of lipids in the vessel ...
On the role of nitric oxide in uterine secretion
(2004-09-24)
Background: Uterine secretion is important in many different aspects of reproduction e.g. sperm transport and survival, fertilization, nourishment of the ovum and implantation. A cholinergic autonomic nervous secretory ...
Anxiety, exhaustion and depression in relation to periodontal diseases
(2006-03-10)
level in GCF was increased, whereas the patients in Study IV surprisingly showed lower cortisol values in GCF than the controls. The level of cortisol in saliva was similar in both groups. Neither did the levels of matrix metalloproteinases-8, -9 (MMP-8...
Alterations in activity and specificity of intracellular proteolysis in disease pathogenesis
(2005-05-17)
The ubiquitin-proteasome pathway (UPP) plays a fundamental role in many basic cellular processes. Virtually all events in cellular physiology include control by the ubiquitin-proteasome pathway. Ubiquitinated substrates ...
PTEN and Akt signalling in Alzheimer’s disease
(2005-11-18)
cortex as compared to control cases. A small but significant decrease in the levels of Ser380PTEN was found in AD medial temporal cortex as shown by dot-blot analysis. Immunohistochemistry of layer III temporal cortex showed the majority of pyramidal...
Viridans group streptococci septicaemia and endocarditis : molecular diagnostics, antibiotic susceptibility and cinical aspects
(2005-04-27)
Viridans group streptococci (VGS) are inhabitants in the oral cavity and in the gastrointestinal tract. They cause severe infections, they are responsible for up to 39 % of the cases of septicaemia in neutropenic patients ...
Long-term neurodevelopmental outcome after moderate neonatal encephalopathy and after post-term birth : two population-based studies
(2006-03-17)
without CP, 20 had cognitive dysfunctions, including learning disabilities, impaired social interaction and executive dysfunctions, and 8 had no impairments. DTI, performed in 9 subjects revealed white matter changes in several regions, including...
Effects of gonadal hormone deficiency on bone mineral density : can physical activity increase bone mineral density in women?
(2006-08-11)
Osteoporosis with its associated fragility fractures is a global health care problem. The incidence of ftagility ftactures has increased dramatically the last 50 years. This has been suggested to at least in part be due ...
Apoptosis in the myelodysplastic syndromes : protective effect of G-CSF
(2005-09-23)
Increased apoptosis of hematopoietic progenitor cells is a hallmark for
the myelodysplastic syndromes (MDS), and one of the main reasons for the
ineffective hematopoiesis and subsequent cytopenia characteristic for ...
Oral health in old age : perception among elderly persons and medical professionals
(2006-09-29)
The general aim of this thesis was to investigate perceptions of oral health among elderly persons and among medical professionals working at primary health care centres. The study samples consisted of elderly persons and ...