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Chemoattractants as causative agents, biomarkers and therapeutic targets in vascular pathology
(2006-09-22)
(SNP) in the CCL11 gene and related the presence of the former to the plasma CCL11 concentrations, measured by ELISA. There were no differences in CCL1 genotype frequencies between patients and controls. Patient G/G carriers had higher circulating CCL11...
Ante partum determination of lactate in amniotic fluid
(2005-05-06)
Background: The present studies were conducted to investigate whether lactate determination in vaginal fluids, 'Lac-test', could be used as a diagnostic test for prelabour rupture of membranes (PROM). To derive the best ...
Biological aspects of synovial fluid mediated aseptic prosthesis loosening
(2005-08-26)
from patients with osteoarthritis, but not in response to aseptic loosening SF. Total protein synthesis in osteoblasts increased after exposure to both types of SF. Procollagen 1 carboxyterminal propeptide (PICP), a marker of collagen synthesis...
Studies on growth hormone induced female-characteristic gene transcription in rat liver
(2005-05-06)
blots confirmed that this transcript was expressed in response to the female-specific GH pattern, and cloning of the full-length cDNA revealed homology to the human serum protein alpha1IB-glycoprotein. The rat a1bg promoter was cloned by 'genome walking...
Studies of the novel PDGFs, focusing on PDGF-D
(2006-05-26)
-D was found. The full-length cDNA encoded a polypeptide of 370 amino acids. The secreted protein turned out to be a disulphide-linked homodimer, which displays a two-domain structure similar to that found in PDGF-C, with an N-terminal CUB domain and a C...
Characterization and modulation of immunoregulatory molecules in neuroinflammation
(2005-01-06)
. The in vitro expression of human TIM-1 and TIM-3 was examined using Th 1 and Th2 cell lines and real time RT-PCR. The ex vivo expression was determined in mononuclear cells derived from peripheral blood (PBMC) and cerebrospinal fluid (CSF-MC) of persons with MS...
On the influence of glia on neurite outgrowth from dopamine neurons in the nigrostriatal system
(2004-11-26)
Interactions between glial cells and neurons are important during fetal development, in the maintenance of the normal functions in tile central nervous system (CNS), arid in response to injuries or diseases. Some of die ...
Tobacco smoking and vertical periodontal bone loss
(2005-05-18)
Cigarette smoking is associated with increased prevalence and severity of destructive periodontal disease in terms of periodontal pocketing, periodontal bone loss, and tooth loss. The smoking destructive effect on periodontal ...
Calcium dynamics and vesicle-release proteins in a prion-infected neuronal cell line
(2005-03-25)
dysfunction in prion diseases. For this purpose I used an immortalized gonadotropin-releasing neuronal cell line (GT1-1) that is susceptible to a mouse-adapted scrapie strain. This cell line represents a suitable system for my studies since the cells possess...
Study of serotonin, innervation and sensory neuropeptides in allergic contact dermatitis
(2005-08-17)
positive epicutaneous patch test reactions, at 72h, an increased number of GAP43 immunoreactive nerve fibres were found in the eczematous compared to control skin. Semiquantification showed an increase in dermal substance P and its neurokinin 1 receptor...