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Chemoattractants as causative agents, biomarkers and therapeutic targets in vascular pathology
(2006-09-22)
Atherosclerosis and restenosis are driven by chronic immune response in the vascular wall. This involves cell migration into and within the vessel wall, cell proliferation as well as accumulation of lipids in the vessel ...
Neutropenic fever during treatment of hematological malignancy : etiology and diagnostics
(2005-01-07)
% were seen for PCT, CRP and IL-6. In the majority of neutropenic fever episodes causative infectious agents cannot be identified. After 3-5 days of fever it has been recommended to reassess anti-microbial therapy. We studied the value of determining...
Maternal morbidity in Uganda : studies on life-threatening pregnancy complications in low-income settings
(2004-11-25)
relations, HIV/AIDS, pregnancy and abortion. Content
analysis was used to describe the findings (Paper 5).
Results: HIV infection was not found to correlate with the risk for PAEM,
HIV-1 seroprevalence 17 (32.7%) among women with PAEM and 38 (36.5%)
among...
Influence of exposure patterns and oxidation in UVR-induced cataract
(2005-04-29)
days and 30 days). In the second study (reciprocity), each rat was exposed to 8 kJ/m2 UVR for a different length of time (5, 7.5, 11, 15, 30, 60, and 120 minutes). In the third study (vitamin E and cataract) rats were fed vitamin E...
Changing reproductive patterns in rural China : the influence of policy and gender
(2005-10-27)
Background: In 1949, at the time for the foundation of the People's
Republic of China, PRC, China had a Total Fertility Rate (TFR) of 5-6
children per woman, and it remained at that level throughout the 1950s
and 1960s. In the beginning of the 1970s...
Regulation of gene and protein expression : two model systems
(2005-11-25)
Genetic information is expressed by DNA transcription and mRNA translation. With few exceptions, every cell of an organism, or the human body, contains the same genetic information. Yet the structure and function of different ...
Leukemia chemotherapy : experimental studies on pharmacological optimisation
(2004-11-26)
Our main goal has been to identify new means to improve chemotherapy of
acute leukaemia:
1. By using low-density lipoprotein (LDL) as a drug carrier to increase
the selectivity of antileukemic drugs, based on high LDL ...
Bad breath : prevalence, periodontal disease, microflora and inflammatory markers
(2005-03-29)
periodontal disease and bad breath demonstrated a higher percentage of teeth with pockets =5 mm than did individuals without bad breath (p<0.001). Moreover subjects with foetor ex ore showed significantly higher levels of plaque and calculus values than did...
Biosynthesis of leukotriene B4 in hematological malignancies
(2005-05-27)
Leukotrienes (LT) are biologically active metabolites of the fatty acid
arachidonic acid (AA). After liberation of AA by phospholipase A 2 (PLA
2), this fatty acid can be converted to leukotrienes, lipoxins,
prostaglandins ...
Distribution of serotonin receptors and transporters in the human brain : implications for psychosis
(2005-04-22)
The serotonin (5-HT) system is thought to be involved in different
psychiatric disorders, including depression and anxiety disorders, and is
a major target for the pharmacological treatment of these conditions. ...