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Chemoattractants as causative agents, biomarkers and therapeutic targets in vascular pathology
(2006-09-22)
Atherosclerosis and restenosis are driven by chronic immune response in the vascular wall. This involves cell migration into and within the vessel wall, cell proliferation as well as accumulation of lipids in the vessel ...
Giardiasis in Leon, Nicaragua : prevalence and protection
(2006-11-20)
to 2 years. Giardia cysts were found in stools of 36.1 % of infants. Among infected children, 24 (21.6 %) acquired the infection before the age of 6 months. Sixty-five children (58.8 %) presented multiples episodes of giardiasis during the first two...
Genetic susceptibility to breast and endometrial cancer
(2004-09-10)
preparations.
We found that a COMT allele that confers high enzyme activity (c.324/474A>G G) was associated with increased risk for lobular breast cancer, but not with breast cancer risk overall. The CYP1B1 variants, c.355G>T, c.4326C>G, and c.4390A>G, were...
Tobacco smoking and periodontal health in a Saudi Arabian population
(2005-09-23)
Arabia, were invited to participate in the study by means of announcements in two daily newspapers. 355 individuals, 100 women and 255 men (17-60 years) responded to a standardized questionnaire and digital panoramic dental radiographs were taken...
Hairdressers : hand eczema, hair dyes and hand protection
(2006-10-06)
-wide retrospective longitudinal cohort study comprising 7,203 female hairdressers attending the vocational hairdressing programme during a period of 25 years. A total of 7,355 women from the general population constituted the control group. A hand rinse method...
Oral mucosal lesions, tobacco use and the long-term outcome in a Swedish population
(2006-11-10)
The overall objectives of this thesis were to study the natural history for Oral Lichen (OLL), Oral Leukoplakia (OL) and Snus Induced Lesions (SIL) and to correlate cancer and mortality among users and non-users of Swedish ...
Tobacco smoking and vertical periodontal bone loss
(2005-05-18)
bone loss was significantly greater in heavy exposure smokers than in light exposure smokers suggesting an exposure-response effect of smoking. Compared to non-smokers the 10-year relative risk was 2.4-fold increased in light exposure smokers and 5.8...
Ribavirin : dose and concentration in treatment of chronic hepatitis C infected patients
(2005-04-29)
viral response was achieved more often in patients with ribavirin concentration above the median concentration of 8.7µM, than below the median. Data are suggesting that higher ribavirin concentrations may lead to better treatment response in genotype 1...
Characterisation of CD8 T cells in mucosa associated lymphoid tissue : implications for immune control of HIV-1 infection
(2006-02-24)
The role of CD8 T cells has been implicated in the partial immune control of HIV-1 infection. Ultimately these cells fail to control the infection and immune deficiency ensues in the absence of antiretroviral therapy. A primary focus of this thesis...
Gastroesophageal reflux disease in adults : the Kalixanda study : a population-based endoscopic study
(2006-12-21)
Gastroesophageal reflux disease (GERD) is a common burden on health care
resources in the Western world and deteriorates the health-related
quality of life of those affected, but its manifestations in the general
population ...