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Chemoattractants as causative agents, biomarkers and therapeutic targets in vascular pathology
(2006-09-22)
Atherosclerosis and restenosis are driven by chronic immune response in the vascular wall. This involves cell migration into and within the vessel wall, cell proliferation as well as accumulation of lipids in the vessel ...
Kostmann syndrome : a clinical and pathophysiological study
(2004-10-15)
Kostmann syndrome or severe congenital neutropenia (SCN) is a rare disease, usually diagnosed during the first months of life, characterized by extremely low levels of neutrophils in the peripheral blood, a maturational ...
Bad breath : prevalence, periodontal disease, microflora and inflammatory markers
(2005-03-29)
Bad breath usually originates within the oral cavity and is believed to be associated with periodontal disease. The over all aim of the present thesis was to study periodontal conditions in subjects with bad breath as well ...
Synthetic studies of marine indole alkaloids and related systems
(2005-11-25)
and 8,9dihydrobarettin, isolated from the marine sponge Geodia baretti. The synthesis of barettin and 8,9dihydrobarettin was performed in this work, involving a highly functionalised arginine derivative. This arginine derivative was used in a peptide...
Posterior capsule opacification and postoperative endophthalmitis following cataract surgery : predictive and protective factors
(2005-04-01)
Modem cataract surgery with implantation of an intraocular lens (IOL) is an increasingly safe and successful procedure, though complications still occur. This thesis addresses the most common complication, posterior capsule ...
Characterisation of CD8 T cells in mucosa associated lymphoid tissue : implications for immune control of HIV-1 infection
(2006-02-24)
The role of CD8 T cells has been implicated in the partial immune control of HIV-1 infection. Ultimately these cells fail to control the infection and immune deficiency ensues in the absence of antiretroviral therapy. A primary focus of this thesis...
The role of incretin peptides and ghrelin in upper gut motility and metabolic control
(2006-11-24)
Metabolic control is essential for the individual and is strictly regulated via a wide range of factors. One important mechanism in maintaining an adequate blood sugar level is the regulation of insulin release and gastric ...
Muscle mitochondria in sepsis
(2006-11-24)
Patients treated in the intensive care unit (ICU) for sepsis induced multiple organ failure often suffer from skeletal muscle fatigue after ICU discharge. Since mitochondria are the main determinants of muscle fatigability, ...
Regulation of carbohydrate metabolism in skeletal muscle during and after contraction
(2006-11-03)
It is well known that exercise increases glucose transport into skeletal muscles. The regulation of this transport, however, is poorly understood. An increased understanding of the mechanisms underlying glucose transport ...
Oral mucosal lesions, tobacco use and the long-term outcome in a Swedish population
(2006-11-10)
The overall objectives of this thesis were to study the natural history for Oral Lichen (OLL), Oral Leukoplakia (OL) and Snus Induced Lesions (SIL) and to correlate cancer and mortality among users and non-users of Swedish ...