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Chemoattractants as causative agents, biomarkers and therapeutic targets in vascular pathology
(2006-09-22)
Atherosclerosis and restenosis are driven by chronic immune response in the vascular wall. This involves cell migration into and within the vessel wall, cell proliferation as well as accumulation of lipids in the vessel ...
Characterization of Eae4 and Eae19-22 in autoimmune neuroinflammation
(2006-02-17)
Multiple Sclerosis (MS) is the most common chronic inflammatory disorders of the central nervous system (CNS) with a prevalence of 1-211000 in the Northern European population. MS is caused by a combination of environmental ...
Evaluation of the infrared reflection method for saccadic eye movement velocity analysis
(2005-12-29)
Saccades are rapid eye movements that change the orientation of the eyes onto objects of interest. In an every day situation saccadic eye movements are used for e.g. reading, scanning objects and enviromnents.
The ...
Alterations in activity and specificity of intracellular proteolysis in disease pathogenesis
(2005-05-17)
The ubiquitin-proteasome pathway (UPP) plays a fundamental role in many basic cellular processes. Virtually all events in cellular physiology include control by the ubiquitin-proteasome pathway. Ubiquitinated substrates ...
Oral mucosal lesions, tobacco use and the long-term outcome in a Swedish population
(2006-11-10)
The overall objectives of this thesis were to study the natural history for Oral Lichen (OLL), Oral Leukoplakia (OL) and Snus Induced Lesions (SIL) and to correlate cancer and mortality among users and non-users of Swedish ...
The role of incretin peptides and ghrelin in upper gut motility and metabolic control
(2006-11-24)
Metabolic control is essential for the individual and is strictly regulated via a wide range of factors. One important mechanism in maintaining an adequate blood sugar level is the regulation of insulin release and gastric ...
Biosynthesis of leukotriene B4 in hematological malignancies
(2005-05-27)
Leukotrienes (LT) are biologically active metabolites of the fatty acid
arachidonic acid (AA). After liberation of AA by phospholipase A 2 (PLA
2), this fatty acid can be converted to leukotrienes, lipoxins,
prostaglandins ...
Platelets and eosinophils in lung tissue remodelling
(2006-08-25)
Tissue injury and inflammation followed by effective repair restores normal function, but defective repair with associated tissue remodelling and fibrosis can lead to loss of organ function. Thus, interactions between ...
Coronary artery bypass surgery without extracorporeal circulation
(2006-03-10)
Introduction: Coronary artery bypass surgery with extracorporeal circulation is associated with a systemic inflammatory response syndrome that contributes to morbidity and mortality. Aortic cross clamping and cardioplegic ...
Evaluation of the DIAGNOdent method for detection and quantification of carious lesions : in vitro and in vivo studies
(2005-03-08)
The sites most susceptible to dental caries are the occlusal surfaces and
the margins of existing restorations. These are also the sites at which
lesion detection by conventional methods is most unsatisfactory. There ...