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Chemoattractants as causative agents, biomarkers and therapeutic targets in vascular pathology
(2006-09-22)
Atherosclerosis and restenosis are driven by chronic immune response in the vascular wall. This involves cell migration into and within the vessel wall, cell proliferation as well as accumulation of lipids in the vessel ...
Modulation of the deubiquitnating system during lymphoid cell activation and viral infection
(2005-08-15)
of hematopoietic origin.
The activity of specific USPs, including USP5, -7, -9, -13, -15 and -22, was upregulated by mitogen activation or virus infection in normal T- and B-lymphocytes. UCH-L1 was highly expressed in several tumor cell lines of epithelial...
Magnetic resonance imaging of rectum : diagnostic and therapy related aspects
(2006-03-31)
-2), and mesorectal volume (NW). Furthermore, the form of PF differed significantly between male and female subjects.
In paper II, we analyzed the influence of MV on the accuracy of the first preoperative MRI. 267 patients with rectal cancer had their MV measured...
Study of serotonin, innervation and sensory neuropeptides in allergic contact dermatitis
(2005-08-17)
In a murine model of contact allergy, 24 h after challenge with antigen, increased axonal growth using an antibody to growth-associated protein-43 (GAP-43) was seen in the epidermis and dermis of eczematous skin. Protein gene product 9.5 (PGP 9.5...
Distribution of serotonin receptors and transporters in the human brain : implications for psychosis
(2005-04-22)
The serotonin (5-HT) system is thought to be involved in different
psychiatric disorders, including depression and anxiety disorders, and is
a major target for the pharmacological treatment of these conditions. ...
Neuromodulation within a spinal locomotor network : role of metabotropic glutamate receptor subtypes
(2004-10-29)
The metabotropic glutamate receptors, mGluRs, are G-protein coupled receptors. They consist of eight cloned subtypes, which are divided into three groups depending on the amino acid sequence similarity, pharmacology and ...
PET studies of the serotonin transporter in the human brain
(2006-10-27)
The serotonin (5-HT) system attracts considerable attention in research on the pathophysiology and drug treatment of neuropsychiatric disorders. The brain imaging technique Positron Emission Tomography (PET) allows for examination...
Tobacco smoking and vertical periodontal bone loss
(2005-05-18)
bone loss was significantly greater in heavy exposure smokers than in light exposure smokers suggesting an exposure-response effect of smoking. Compared to non-smokers the 10-year relative risk was 2.4-fold increased in light exposure smokers and 5...
Local and systemic inflammatory mediators and their relation to pressure-pain threshold and pain of the temporomandibular joint
(2006-11-17)
condyle with a hand-held electronic pressure algometer (Somedic Production AB, Sollentuna, Sweden). TMJ pressure-pain threshold is systemically modulated and not modulated by the investigated inflammatory mediators (5-HT, TNFα, IL-1sRII) in the TMJ...
Characterization of ERp29 : a novel secretion factor of endoplasmic reticulum
(2005-04-29)
ERp29 is a ubiquitously expressed endoplasmic reticulum protein strongly
conserved in mammalian species. The N-terminal domain of ERp29 is similar
to the thioredoxin domain of protein disulfide isomerase (PDI) lacking
however ...