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Chemoattractants as causative agents, biomarkers and therapeutic targets in vascular pathology
(2006-09-22)
plaques, where it colocalized with macrophages, endothelial cells, and smooth muscle cells (SMC). Human coronary artery SMC exposed to either the LTB4 Or the BLT1 partial agonist U75302 exhibited increase of whole-cell ion currents indicating...
Evaluation of isovolumic myocardial motions in human subjects using tissue velocity echocardiography
(2006-03-17)
Colour-coded tissue velocity imaging (TVE) with Echocardiography is an established method for evaluation of the global cardiac function and of the regional myocardial movements. The TVE-technique allows measurements of ...
Nutritional status and cognitive function in frail elderly subjects
(2004-08-13)
weight gain of 3.4 ±11.2 kg (p=0.00 1) 6 months later, that was not seen in the control group. The weight gain was not related to an improvement in ADL capacity or cognitive function (MMSE). A BMI <23 was noticed in more than half of 231 patients admitted...
Viral zoonoses in Estonia : hantaviruses and tick-borne encephalitis virus : identification, prevalence, serological and genetic relationships
(2006-02-15)
prevalence rates to SAAV were found on Saaremaa and Vormsi islands (23,1% and 7,3% respectively) and to PUUV in the central/south-western parts of Estonia (up to 18,4% in Raplamaa county). The relatively high prevalence suggested that a significant number...
Fusion activation in murine leukemia virus
(2006-04-21)
This thesis describes the fusion activation in Murine leukaemia virus (MLV). During entry of retroviruses into uninfected cells, the viral and cellular membranes fuse. The fusion process is mediated by the viral envelope ...
Impaired glucose tolerance in ischemic heart disease
(2005-11-18)
Background: Diabetes mellitus (DM) and impaired glucose tolerance test
(IGT) are well known risk factors for cardiovascular disease (CVD).
Individuals with IGT, a prediabetic state, are asymptomatic during many
years ...
alpha-Melanocyte-stimulating hormone in neurodegenerative processes
(2006-01-20)
The fact that inflammatory processes accompany the neuronal cell death in most neurodegenerative disorders, has in recent years inspired to studies on the role of inflammation in the brain and the possibility to prevent ...
Immunological and virologica response to antiretroviral treatment (art) in patients infected with different HIV-1 genetic subtypes
(2006-02-17)
similarly.
Paper II: Other parameters of immune activation that we have evaluated are IL-7 and its receptor. The expression of the EL-7Ralpha, in T cells from HIV-1 patients was studied in relation to CD4+T cell counts, IL-7 concentration, T cell...
Studies on growth hormone induced female-characteristic gene transcription in rat liver
(2005-05-06)
of the transcription factors C/EBPalpha, Stat5, HNF4 and HN176. However, there is no evidence that these factors transduce the sex-specific expression of the gene.
We used the subtractive suppressive hybridization (SSH) technique to identify additional genes...
Biosynthesis of leukotriene B4 in hematological malignancies
(2005-05-27)
Leukotrienes (LT) are biologically active metabolites of the fatty acid
arachidonic acid (AA). After liberation of AA by phospholipase A 2 (PLA
2), this fatty acid can be converted to leukotrienes, lipoxins,
prostaglandins ...