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Chemoattractants as causative agents, biomarkers and therapeutic targets in vascular pathology
(2006-09-22)
Atherosclerosis and restenosis are driven by chronic immune response in the vascular wall. This involves cell migration into and within the vessel wall, cell proliferation as well as accumulation of lipids in the vessel ...
Motion analysis of the knee : kinematic artifacts, EMG normalisation and joint forces
(2005-04-25)
joint forces, and insufficient measurement accuracy of 3D knee joint kinematics.
The aim of this thesis is to address some of these issues by: (1) evaluating techniques of electromyography (EMG) analysis with ACL patients; (2) investigating...
Prevention and treatment of hepatitis B virus infection
(2005-05-06)
-alpha 5 MIU/m2 body surface area subcutaneously three times weekly for 20 weeks and followed up over a 2-year period. Response with seroconversion and HBV DNA loss in serum occurred in two children (genotypes A and D, respectively), both with pre...
The effects of some peptide hormones on osteoblast-like cells : with specific focus on oxytocin and vasopressin
(2005-01-07)
studies was to investigate the effects of OXT and AVP on OBlike cells. Primary cultures of human OB-like (hOB) cells were prepared from trabecular bone material obtained during knee- and hip-joint replacement surgery. An osteosarcoma cell line (SaOS-2...
Kvinnohälsa i perspektiv : studier med barnmorskor och läkare samt med kvinnor som vårdbrukare : exempel från cervixcancerscreening och obstetrisk vård av omskurna kvinnor
(2005-05-06)
In this thesis two areas of women's health are examined from different
stakeholder perspectives. The areas are cervical cancer screening (CCS;
articles I, III, V) and obstetrical care of circumcised/infibulated ...
Hantaviruses : animal models, immunology and pathogenesis
(2004-11-18)
's induced
strong immune responses, only rDOBV N given with Freund's adjuvant
protected against virus challenge, suggesting that the strong anti-N
protein T helper 2 type of immune response induced by Alum is not
protective in mice.
Infection of suckling...
Leukotriene A4 hydrolase : studies of structure-function relationships by site-directed mutagenesis and X-ray crystallography
(2004-10-15)
. Furthermore, protein-ligand
interactions are confirmed by the LTA4H-HACAP crystal structure complex
at 2.0 A resolution....
Biosynthesis of leukotriene B4 in hematological malignancies
(2005-05-27)
Leukotrienes (LT) are biologically active metabolites of the fatty acid
arachidonic acid (AA). After liberation of AA by phospholipase A 2 (PLA
2), this fatty acid can be converted to leukotrienes, lipoxins,
prostaglandins ...
On gallstone disease : complications and surgical treatment
(2005-11-18)
Background: Gallstone disease is an important cause of morbidity in the Western world. Symptomatic gallbladder stones have been managed by cholecystectomy since 1882. After the introduction of laparoscopic cholecystectomy ...
Synthetic studies of marine indole alkaloids and related systems
(2005-11-25)
-carboxaldehyde and 1,4-diacetyl-2,5-piperazinedione ill the presence of caesium carbonate. Several analogues of dipodazine, together with a few barettin analogues have been prepared and tested for activity ill antifouling assays, results and relevance of which...