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On spinal mechanisms for reflex control in man : modulation of Ia-afferent excitation with changes in muscle length, activation level and fatigue
(2004-03-26)
To control muscle force, neural activation has to take alterations in
muscle mechanics into account. This thesis assesses modulations in
excitatory efficacy of Ia-afferents during muscle length changes at
different ...
Experimental studies on effects of orthodontic forces in generation of immune responses : possible roles for immunoregulating molecules in the control of alveolar bone remodeling
(2004-08-05)
, TNF-alpha, IFN-gamma and
the anti-inflammatory cytokines IL-4 and IL-10 was examined. Also, the
expression of potential chemokines as macrophage inflammatory protein-2
(MIP2), monocyte chemotactic protein-1 (MCP-1), and Regulated upon
Activation...
Molecular mechanisms involved in the growth of human uterine leiomyomas
(2002-11-14)
uterus by using cDNA-microarray. Five interesting genes were putatively estrogen-responsive in the uterus, including Fas-activated serine/threonine kinase (FAST), CD24, thymosin beta4, follistatin-related protein (FSRP) and thy-1 protein. We hypothesize...
Synthesis of heterocycles from anthranilic acid and its derivatives
(2004-05-07)
quinazolines, a type of heterocyclic compounds that is considered to be highly interesting as scaffolds for development of new drugs. When the acyl halide was a tertiary 2-haloacyl halide, the reaction instead gave 1,4-benzodiazepine-3-ones via rearrangement...
Diagnostic evaluation of fetal death with special reference to intrauterine infections
(2002-05-10)
The incidence of intrauterine fetal death (>=28 gestational weeks) is approximately 4/1000 births in Sweden. In order to arrive at a potential cause of death, a number of investigations have been recommended in the diagnostic evaluation...
Diabetic osteopathy : a study in the rat
(2012-03-09)
-I was reduced by 18%, while IGFBP-1 and IGFBP-4 were increased by 89 and 20 %, respectively. This complies with the lower BMD in the diabetic rats. In cortical bone, IGF-I was reduced by 38%, whereas no change was seen in ankles. The loss of IGF-I in cortical...
The transcription machinery in schizosaccharomyces pombe and its regulation
(2004-04-28)
contains 4 additional proteins, TRAP230, TRAP240, Srb10 and Srb11, which are absent in PC2/CRSP. We developed a purification scheme for the larger form of the S. pombe Mediator using the so-called tandem affinity purification tag (TAP). Our new purification...
Mild cognitive impairment neuroimaging markers for early diagnosis of dementia
(2003-09-12)
This thesis concerns the investigation of mild cognitive impairment (MCI) and Alzheimer's disease (AD) using single photon emission computed tomography (SPECT) and quantitative electroencepholography (qEEG).
In study ...
Retinoids in experimental neuroblastoma therapy
(2003-01-24)
Retinoids are analogues of vitamin A, with documented activity against various malignant cell types. Neuroblastoma is a childhood tumour of the sympathetic nervous system that shows a complex clinical and biological ...
The embodied experience of living with Parkinson’s disease
(2003-05-16)
People with Parkinson’s disease (PD) face many continuous limitations in daily life because of their illness. To illuminate the lived experience of PD and to evaluate ways to give individuals who suffer from PD comprehensive ...