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Muscarinic M1 and M4 receptor subtypes in normal and pathological conditions in the central nervous system : studies on human and animal tissues using subtype selective ligands
(2003-08-20)
Snake venoms from different mamba species contain toxins that bind to muscarinic acetylcholine receptors (mAChR). The toxins MT-1 (selective for M1 after iodination), M1 toxin-1 (also known as MT7, selective for MI) and ...
Back pain post partum : clinical and experimental studies
(2003-03-07)
Background: Half or more of pregnant women experience back pain at some time during pregnancy. Even though back pain exists post partum, it is not well documented and detailed studies concerning different back pain ...
Passive immunization against oral pathogens
(2004-05-21)
Dental caries is one of the most common infectious diseases and Streptococcus mutans (S. mutans) is considered to be the main etiological agent of dental caries. S. mutans possesses a variety of virulence factors that ...
Vestibular control of body orientation in lamprey
(2004-03-26)
Maintenance of body orientation (postural control) is a vital motor function of the brain. The general goal of this project was to understand the organization and operation of neuronal networks responsible for postural ...
Circulating immune complexes in atherosclerotic vascular disease
(2001-08-31)
We have investigated the association of the humoral immune factors
circulating immune complexes (CICs) and autoantibodies against
cardiolipin (aCL) and oxidatively modified LDL (oxLDL) to atherosclerotic
vascular diseases.
In ...
Local recurrence after breast conserving surgery in breast cancer
(2002-08-30)
. Generally, the risk of local recurrence was higher than expected, but the estimated survival rates were gratifying. The overall risk of local recurrence was 9.2% at five years and 21.1% at ten years, and the breast cancer-specific survival was 93.3% and 85...
Nursing documentation in clinical practice : instrument development and evaluation of a comprehensive intervention programme
(2002-09-27)
The purpose of this study was to describe and analyse effects of a two-year comprehensive intervention concerning nursing documentation in patient records when using the VIPS model - a model designed to structure nursing ...
Identification of the common eliminated region (CER1) by the microcell hybrid based 'elimination test'
(2001-11-27)
The aim of elimination test (Et) is to identify tumor antagonizing genes
from chromosome regions that are regularly deleted in microcell hybrid
(MCH) derived tumors through serial SCID mice passages. Et so far was
focused ...
Studies on the inflammatory response in experimental acute pyelonephritis and its importance for the development of renal scarring
(2002-01-08)
Acute pyelonephritis especially in childhood is a serious and globally common bacterial infection. The infecting microorganism is often derived from the patient's own bowel flora and mainly affects the renal parenchyma and ...
Enhancement of HIV-1 DNA immunogens
(2002-11-14)
Human immunodeficiency virus type 1 eludes control by the immune response through a high degree of variability and immune escape mechanisms. Induction of a broad specific immune response is important to clear virus-infected ...