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Hormone therapy and the breast : aspects on proliferation, apoptosis and mammographic density
(2004-05-14)
Breast cancer is the major malignancy among women in the western world. The breast is clearly a target organ for sex steroid hormones and hormonal treatments have been associated with an increased risk of breast cancer. ...
Depression, coronary artery disease and change of lifestyle
(2001-11-29)
Depression has been identified as a risk factor for the development of coronary artery disease (CAD) and has been associated with functional impairment and disability, poor outcome of lifestyle changes, incomplete and ...
Atherosclerosis of the ascending aorta as a risk factor for stroke after cardiac surgery : a study based on epiaortic ultrasound
(2004-04-23)
% of the ascending aorta diseased and those with more than 50% affected
were 95.3±0.9%, 91.8±2.1% and 65.0±14.6%, respectively (p<0.0001). The
distal-left side of the ascending aorta was associated with a 5-fold
increase in 5-year stroke rate.
Conclusions...
Genetic studies of susceptibility to diabetes mellitus with emphasis on type 1 diabetes
(2003-05-02)
2p (p = 9 x 10-4), 5p11-q13 (p = 8 x 10-4), and 16p (p = 2 x 10-4). The region on chromosome 2p includes the EIF2AK3 gene, which has been implicated in a rare form of very early onset insulin-dependent diabetes. However, association to T1DM...
Regulation of T cell activation and death by the affinity of TCR for peptide/MHC complexes
(2002-05-15)
cells. In contrast to classical AICD, death receptors are not essential for the elimination of CTLs activated with partially agonistic peptides. In addition, death receptor independent apoptosis requires caspases other than caspase 3 and 8. Induction...
Birth centre care : reproduction and infant health
(2004-04-02)
This thesis has two general aims, to investigate factors affecting
women s decision to have a second baby and to study the effect of birth
centre care on infant outcome. The specific aims were to investigate 1)
whether ...
Towards elimination of anal-sphincter and rectal dysfunction after radiation therapy for prostate cancer
(2004-05-07)
/29) of the patients irradiated using 4 fields with a multi-leaf collimator and 20 percent (8/40) of the patients treated using 3 fields (one AP, two lateral) without multi-leaf collimator. Seven out of 29 patients (24%) treated with 4-field reported diarrhea or loose...
Radiologic diagnosis of appendicitis in children
(2004-04-23)
Suspected appendicitis is the most common cause of emergency abdominal surgery in children. Because of the often atypical clinical findings, the diagnosis of appendicitis is difficult and may be delayed. Perforation has ...
Sacroiliac pain-provocation testing in physiotherapy : time and force recording
(2004-08-27)
Introduction: Some of the tests used for examining pain arising from the
sacroiliac region are intended to provoke pain by using manually applied
forces. Previous reliability and validity studies of sacroiliac
pain-provocation ...
HLA predisposition to human papillomavirus induced cervical neoplasia : population based studies from the Västerbotten county in northern Sweden
(2001-08-08)
Infection with human papillomaviruses (HPV) types 16 and 18 is the major
cause of cervical neoplasia. Although a high proportion of cervical
cancers (CXCA) harbor HPV genomes, only a small number of women infected
with ...