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Management of Helicobacter pylori infection in Vietnam
(2004-05-07)
-daily with PPI group and 95.3% in the standard therapy group. Overall reinfection with H. pylori one year following successful eradication was 23.5% and 89.8% of the patients were free of peptic ulcer disease. In the patients who were not successful treated, 85.1...
In vitro studies of retinoids and arsenic in non-M3 acute myeloid leukemia
(2002-11-08)
promyelocytic leukemia (APL) and both drugs exhibit less toxic effects than the commonly used chemotherapeutic drugs.
In these studies we have investigated the effects of retinoids and arsenic in cells from patients with non-APL (or non-M3) AML. Furthermore...
Immunogenetic studies in autoimmune endocrine diseases
(2003-11-25)
autoimmune process. The strongest genetic association identified is that with HLA class II genes located on the short arm of chromosome 6. It is well known that both HLA DRB1*04-DQA1*0301DQB1*0302 (DR4-DQ8) and DRB1*03DQA1*0501-DQB1*0201 (DR3-DQ2...
Invasion promoting factors in endometriotic and endometrial tissue
(2004-05-14)
Endometriosis is a common gynaecologic disorder, affecting women of fertile age with pelvic pain and infertility, and is characterized by the presence of endometrial glands and stroma outside the uterine cavity. Retrograde ...
Molecular epidemiology of hepatitis A and hepatitis B virus in central America
(2002-04-17)
160, corresponding to the putative new subtype adw3. This is also the first report on strains encoding d-specificity within genotype D known to encode ayw2, ayw3 and rarely ayw4. In conclusion HAV strains circulating in CA were found to belong...
Autoimmune markers in autoimmune diabetes
(2003-12-19)
Type 1 diabetes mellitus (T1DM) is an autoimmune disease, characterized by autoimmune mediated loss of insulin secreting Beta-cells. The disease is associated with certain HLA class 11 haplotypes. HLA DR3-DQ2 and DR4-DQ8 are positively while DQ6...
Malignant mesothelioma : an experimental study with emphasis on proteoglycans in mesothelial cell growth and differentiation
(2002-04-17)
Malignant mesothelioma is a highly aggressive tumor with median survival ranging from 4 to 12 months and, despite intense therapeutical efforts, it is invariably fatal. Mesothelioma cells are unique in the sense that they ...
The importance of Escherichia coli fimbriae in urinary tract infection
(2001-11-16)
Urinary tract infection (UTI) is a major bacterial infectious disease among women. Uropathogenic Escherichia coli is the most dominant causative agent. Clinical observations indicate that repeated cystitis induces a ...
Nuclear hormone receptors studied by molecular dynamics computer simulations
(2004-03-05)
Nuclear hormone receptors form a super family of homologous transcription factors. The liganddependent nuclear receptors are important drug targets controlling metabolic and inflammatory disorders, amongst others. The ...
Cellular immunity and inflammation in atherosclerosis
(2001-11-09)
Atherosclerosis, the major cause of death and disability in western countries, is nowadays recognized as an inflammatory disease. Low density lipoprotein (LDL), the major carrier of cholesterol in plasma, is trapped in the ...