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Human ovarian follicle recruitment : an in vitro approach
(2004-03-17)
matrix in defined media for
7 and 14 days at 37°C with 5% C02. Different culture medium supplements
were investigated including growth differentiation factor-9 (GDF-9),
8-bromo cyclic GMP (cGMP), and activin A alone or in combination with
follicle...
Voltage sensor movements in shaker and HCN channels
(2003-11-14)
is located more than 20 A away from a residue 418C in the pore domain in the resting state, and that it moves close to (8 Å) the pore residue during channel activation.
2. The voltage sensor S4 of an HCN channel was shown to move in a similar way as S4...
Pathogenetic studies of adjuvant-induced arthritis
(2002-11-15)
Rheumatoid arthritis (RA) is a disabling chronic inflammatory disease, presumably autoimmune, that progressively destroys peripheral joints. The etiopathogenesis remains largely unknown, and an understanding of disease ...
Direct and phagocyte-mediated lipid peroxidation of lung surfactant by group B streptococci and other bacteria : protective effect of antioxidants
(2002-09-06)
Respiratory distress syndrome (RDS), caused by surfactant deficiency, is a leading cause of mortality and morbidity in preterm neonates. Further, infants with systemic neonatal infection or pneumonia often have signs of ...
Studies on autoimmune diabetes in Latvians and other populations
(2001-10-09)
alleles. IDDM is positively associated with HLA DR3 and DR4 in Caucasians. From HLA-DQ molecules, DQ8 (DQA1*0301- DQB1*0302) is the most prevalent IDDM haplotype in Caucasians, followed by DQ2 (DQA1*0201-DQB1*0501). Taken together, DQ8, DQ2 or both account...
Birth centre care : reproduction and infant health
(2004-04-02)
This thesis has two general aims, to investigate factors affecting
women s decision to have a second baby and to study the effect of birth
centre care on infant outcome. The specific aims were to investigate 1)
whether ...
Severe hypoxemia during apnea in humans : influence of cardiovascular responses
(2002-09-13)
When a diving human holds his or her breath, the heart beat slows and the blood vessels constrict in large portions of the body. In diving mammals such as seals, similar responses effectively conserve oxygen for the brain, ...
Hepatitis C virus kinetics during antiviral treatment
(2004-03-05)
It is estimated that 170 million individuals have chronic hepatitis C virus (HCV) infection, whereof 20-30% will develop end stage liver disease within 20-30 years. Antiviral therapy can stop this deterioration and clear ...
Hepatitis C in chronic kidney disease and kidney transplantation : with special reference to epidemiology and treatment
(2003-10-31)
Hepatitis C (HCV) is a clinical problem in infected kidney transplant patients but is also a cause of renal disease and vasculitis. Standard therapy for HCV is a combination of interferon and ribavirin. Renal patients have ...
Radiologic diagnosis of appendicitis in children
(2004-04-23)
Suspected appendicitis is the most common cause of emergency abdominal surgery in children. Because of the often atypical clinical findings, the diagnosis of appendicitis is difficult and may be delayed. Perforation has ...