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Molecular cloning and characterization of the murine acyl-CoA thioesterase CTE-I
(2004-04-23)
Mouse cytosolic type I acyl-CoA thioesterase (CTE-I) is a member of the
type I family of acylCoA thioesterases. These enzymes hydrolyze acyl-CoAs
to non-esterified fatty acids (NEFAs) and Coenzyme A (CoA-SH) and are
strongly ...
Vector development for suicide gene therapy
(2002-05-03)
-mediated integration in several cultured cell lines as well as
primary human donor T-lymphocytes (Paper IV).
We have prepared suicide gene therapy vectors containing HSV-tk and OuaR
selection marker fusion gene in extensively optimised retroviral backbone
SF91...
Description and prediction of clinical radiosensitivity : emphasis on normal tissue reactions
(2004-02-27)
.009 and p = 0.034, respectively). Responding patients thus had an
increased G2 phase accumulation in comparison with non-responders.
From a cohort of 177 breast cancer patients, 16 patients (9%) developed
severe early lung reactions after RT...
Dissection of immunity controlling spread and growth of Listeria monocytogenes in neuronal cells
(2003-11-07)
Listeria monocytogenes is a Grain-positive, facultative intracellular bacterium that causes severe infections in the nervous system of domestic animals and humans. Rhombencephalitis (brainstem encephalitis) due to L. ...
O6-methylguanine-DNA-methyltransferase and DNA mismatch repair in relation to drug resistance in malignant melanoma
(2004-03-26)
-based chemotherapy in melanoma. However, a higher frequency of LOH was observed at the specific loci, 3p23, in non-responders 5/9 (56%) vs. 1/7 (14%) responders, and 11q23, which occurred in 4/9 (44%) of non-responders compared to 115 (20%) of responders....
Tuberculosis and HIV interaction in Ethiopian children : aspects on epidemiology, diagnosis and clinical management
(2002-08-30)
the controls (AOR 12.7; 95% Cl 2.9,55).
The second study explores possible background features associated with
dual infection. These were young age, high educational level of mothers,
having lost one or both parents and being BCG vaccinated. The findings...
Synthesis of heterocycles from anthranilic acid and its derivatives
(2004-05-07)
Anthranilic acid (2-aminobenzoic acid, Aa) is the biochemical precursor to the amino acid tryptophan, as well as a catabolic product of tryptophan in animals. It is also integrated into many alkaloids isolated from plants. ...
Sacroiliac pain-provocation testing in physiotherapy : time and force recording
(2004-08-27)
Introduction: Some of the tests used for examining pain arising from the
sacroiliac region are intended to provoke pain by using manually applied
forces. Previous reliability and validity studies of sacroiliac
pain-provocation ...
Circulating immune complexes in atherosclerotic vascular disease
(2001-08-31)
We have investigated the association of the humoral immune factors
circulating immune complexes (CICs) and autoantibodies against
cardiolipin (aCL) and oxidatively modified LDL (oxLDL) to atherosclerotic
vascular diseases.
In ...
Passive immunization against oral pathogens
(2004-05-21)
Dental caries is one of the most common infectious diseases and Streptococcus mutans (S. mutans) is considered to be the main etiological agent of dental caries. S. mutans possesses a variety of virulence factors that ...