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Pharmacogenetics of human cytochrome P450 3A (CYP3A) enzymes
(2003-10-24)
The cytochrome P450 3A (CYP3A) subfamily encompasses the most important CYP enzymes with respect to drug metabolism, in particular CYP3A4. responsible for the metabolism of a majority of drugs being metabolized in order ...
The relation of blood pressure to dementia in the elderly : a community-based longitudinal study
(2004-01-09)
This doctoral thesis concerns a community-based, prospective study aimed
at investigating the complex relationship between blood pressure (BP) and
risk of dementia in a dementia-free cohort (n = 1301) aged >=75 years ...
The human placenta : an angiographic study
(2003-04-25)
The arterial vessels from the umbilical cord spreading over the chorion and its cotyledonary branches constitute the main body of the placental vascular tree. In the present study it was visualized by angiography and related ...
Synthesis of heterocycles from anthranilic acid and its derivatives
(2004-05-07)
products were more or less complex 1,3-benzoxazinones, one of which required X-ray crystallography confirm its structure. During the work on preparation of N-substituted derivatives of Aa, necessary for synthesis of 1,4-benzodiazepine-3,5-diones...
Radiologic diagnosis of appendicitis in children
(2004-04-23)
Suspected appendicitis is the most common cause of emergency abdominal surgery in children. Because of the often atypical clinical findings, the diagnosis of appendicitis is difficult and may be delayed. Perforation has ...
Minimally invasive hernia surgery
(2003-04-25)
Minimally invasive laparoscopic and open tension-free techniques have been evolved during the 1990's. Different laparoscopic techniques have been used, where the totally extraperitoneal hernioplasty (TEP) is a technically ...
Intestinal functions in animals : an experimental study on horses, pigs, cows and fish
(2001-11-07)
Animals and humans live in symbiosis with an active gastrointestinal
ecosystem. The balance of the system is maintained by the main actors,
the macroorganism, the microflora and the environment, in concert.
Microflora ...
Microfluidic analysis and parallel confocal detection of single molecules
(2003-09-12)
) was utilized to investigate hydrodynamic pressure driven flow in microchannels with a cross section of 50 x 50 µm2. The flow itself, was detected non-altered or noninvasively, since only tiny (a couple of nanometer in size) dye-molecules were entrained...
In silico prediction of CIS-regulatory elements
(2004-04-19)
As one of the most fundamental processes for all life forms, transcriptional regulation remains an intriguing and challenging subject for biomedical research. Experimental efforts towards understanding the regulation of ...
Risk characterization of familial cancer using the Swedish family-cancer database with a special reference to breast cancer
(2003-11-07)
This thesis reports on epidemiological studies on family related cancer in Sweden. The Family-Cancer Database was constructed in 1996 from several national registries. Family relations were available from the Generation ...