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Natural and induced immunity against the tumour-associated antigen, Ep-CAM
(2003-11-27)
The tumour-associated antigen (TAA), Ep-CAM is overexpressed on various human carcinomas, including colorectal carcinoma (CRC). TAAs or their immunodominant epitopes that are spontaneously recognised by the immune system ...
Socio-economic consequences of longstanding illness
(2002-08-09)
This thesis focuses an old research area of social medicine, the social and economic consequences of chronic illness and factors modifying this effect. Historically, illness was the main predictor of poverty. Since then, ...
Studies on head trauma complications with special reference to mild traumatic brain injury
(2004-03-05)
found evidence that TBI is not a risk factor for brain tumour (SIR 1.0
(Cl 0.9-1.2))....
New evidence on germ-cell testicular cancer aetiology
(2004-01-09)
and later periods in life, such as childhood and adolescence, are important time windows for determining lifetime risk for testicular cancer.
A case-control study, including 3,051 cases and 9,007 controls born in Sweden after 1940, was carried out using...
Studies on uptake and effect of triclosan on production of inflammatory mediators in human gingival fibroblasts
(2003-11-21)
Triclosan (2,4,4'-trichloro-2'-hydroxy-diphenyl ether) is a lipid soluble anti-bacterial agent widely used in dentifrices, mouthrinses, soap and cosmetics. Although reports on the efficacy of triclosan on periodontal ...
Neuropeptide release in the rat dorsal horn in models of persistent pain : effects of opioids
(2002-05-03)
Nerve injury and tissue inflammation may lead to exaggerated responses to both noxious stimuli (hyperalgesia) and innocuous stimuli (allodynia). Altered release pattems of neurotransmitters in the dorsal hom of the spinal ...
Synthesis of heterocycles from anthranilic acid and its derivatives
(2004-05-07)
Anthranilic acid (2-aminobenzoic acid, Aa) is the biochemical precursor to the amino acid tryptophan, as well as a catabolic product of tryptophan in animals. It is also integrated into many alkaloids isolated from plants. ...
Malignant mesothelioma : an experimental study with emphasis on proteoglycans in mesothelial cell growth and differentiation
(2002-04-17)
Malignant mesothelioma is a highly aggressive tumor with median survival ranging from 4 to 12 months and, despite intense therapeutical efforts, it is invariably fatal. Mesothelioma cells are unique in the sense that they ...
Lower limb ischemia in women
(2004-02-27)
Arteriosclerosis is a general disease affecting different parts of the arterial system. In coronary heart disease (CHD) women have different risk factors, symptoms, indication for treatment, interpretation of diagnostic ...
Intoxication of mammalian cells by the cytolethal distending toxin of Haemophilus ducreyi : a novel mechanism of action
(2001-09-14)
The cytolethal distending toxins (CDTs) are a newly described family of
bacterial protein toxins with a novel mechanism of action: DNA damage.
Haemophilus ducreyi produces a cytotoxin that belongs to this family.
This ...