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Chemoattractants as causative agents, biomarkers and therapeutic targets in vascular pathology
(2006-09-22)
Atherosclerosis and restenosis are driven by chronic immune response in the vascular wall. This involves cell migration into and within the vessel wall, cell proliferation as well as accumulation of lipids in the vessel ...
Immunodominant proteins in Giardia lamblia
(2004-11-19)
The protozoan parasite Giardia lamblia is a major cause of diarrhoea in
humans and other mammals. Infection starts by ingestion of infectious
cysts that excyst in the upper part of the small intestine and attach ...
Prediction of function shift in protein families
(2006-08-14)
With the availability of a large number of complete genome sequences, it has become essential to annotate the protein sequences derived from them as precisely as possible. Even though presently available computational ...
Genetic association analysis of overlapping biological pathways in cardiovascular and Alzheimer disease
(2006-05-26)
To gain insight into the importance of the genome for diseases, sequencing and genotyping efforts aim to identify the consequences of genetic variation on both a functional and population level. The task involves the ...
Transoesophageal and transthoracic recordings of mitral annulus motion
(2006-02-03)
Maximal systolic and diastolic velocities recorded from four sites of the mitral annulus motion (MAM) reflect left ventricular (LV) performance. This thesis focus on factors influencing M-mode derived velocities in healthy ...
Physical activity, body composition and physical self esteem among children and adolescents
(2005-02-25)
The increasing prevalence of overweight and obesity poses a global health problem. Special concern is focused on overweight during youth since it may cause negative impact on health both during childhood, adolescence and ...
Physical fitness and overweight in Swedish youths
(2005-03-22)
The aim of the present thesis was to describe the level of physical fitness and prevalence of overweight and obesity in Swedish youths, and their trends over 14 years. Additionally, the relation between fitness and overweight ...
Child health promotion : analyses of activities and policy processes in 25 Swedish municipalities
(2005-09-30)
The Swedish municipalities are important actors that offer appropriate
environments for healthpromoting activities directed at children and
adolescents. Enhanced understanding on how such activities develop is
needed ...
Synthesis of indole and oxindole derivates incorporating pyrrolidino, pyrrolo or imidazolo moieties
(2004-11-26)
The focus of this thesis is on the synthesis of oxindole- and indole-derivatives incorporating pyrrolidins, pyrroles or imidazoles moieties.
Pyrrolidino-2-spiro-3'-oxindole derivatives have been prepared in high ...
Diabetes, physical activity and endometrial cancer
(2006-11-22)
Accumulating evidence suggests that hyperinsulinemia, in the context of insulin resistance, is associated with carcinogenesis. Physical activity is involved in the regulation of metabolic and hormonal pathways and is an ...