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Chemoattractants as causative agents, biomarkers and therapeutic targets in vascular pathology
(2006-09-22)
Atherosclerosis and restenosis are driven by chronic immune response in the vascular wall. This involves cell migration into and within the vessel wall, cell proliferation as well as accumulation of lipids in the vessel ...
Regression on high-dimensional predictor space : with application in chemometrics and microarray data
(2004-11-26)
This thesis focuses on regression methodology for prediction and
classification in situations where there are many predictors but limited
number of observations. This situation is common in chemometrics and
microarray ...
Urinary leakage and physical activity in young women
(2005-11-18)
The effect of recreational physical activity on urinary leakage/ incontinence (UL/UI) with regard to load on the pelvic floor (PF) in young women has not been studied specifically.
The aim of the present work was, ...
Dietary supplements : trends, demographics and mortality among users
(2004-11-05)
to cardiovascular diseases and 398 deaths due to
cancer during 153,796 person-years of follow-up for the specific cause
mortality. In the multivariate adjusted model, there was no association
observed between use of dietary supplements and all-cause mortality...
Immunological and virologica response to antiretroviral treatment (art) in patients infected with different HIV-1 genetic subtypes
(2006-02-17)
months of treatment, while the corresponding figures for Caucasians and Asians were 91% and 100%, respectively. We found a good short-term virological outcome of ART in a cohort of ART-naive patients of diverse ethnic background infected with different...
Synthetic studies of marine indole alkaloids and related systems
(2005-11-25)
and 8,9dihydrobarettin, isolated from the marine sponge Geodia baretti. The synthesis of barettin and 8,9dihydrobarettin was performed in this work, involving a highly functionalised arginine derivative. This arginine derivative was used in a peptide...
Genetic association analysis of overlapping biological pathways in cardiovascular and Alzheimer disease
(2006-05-26)
lies in proximity to an AD linkage peak on chromosome 9q, making ABCA1 both a biological and positional candidate. In four independent European populations, significant differences in genotype frequencies were found between cases and controls indicated...
Biosynthesis of leukotriene B4 in hematological malignancies
(2005-05-27)
Leukotrienes (LT) are biologically active metabolites of the fatty acid
arachidonic acid (AA). After liberation of AA by phospholipase A 2 (PLA
2), this fatty acid can be converted to leukotrienes, lipoxins,
prostaglandins ...
Anxiety, exhaustion and depression in relation to periodontal diseases
(2006-03-10)
level in GCF was increased, whereas the patients in Study IV surprisingly showed lower cortisol values in GCF than the controls. The level of cortisol in saliva was similar in both groups. Neither did the levels of matrix metalloproteinases-8, -9 (MMP-8...
The role of incretin peptides and ghrelin in upper gut motility and metabolic control
(2006-11-24)
Metabolic control is essential for the individual and is strictly regulated via a wide range of factors. One important mechanism in maintaining an adequate blood sugar level is the regulation of insulin release and gastric ...