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Diet and ovarian cancer : a population-based cohort of 60 000 women
(2005-05-06)
% confidence intervals (CIs), while
adjusting for potential confounders. All statistical tests were
two-sided. From March 1987 through June 2004, we ascertained 288 incident
cases of invasive epithelial ovarian cancer, including 135 serous ovarian
cancers...
Chemoattractants as causative agents, biomarkers and therapeutic targets in vascular pathology
(2006-09-22)
Atherosclerosis and restenosis are driven by chronic immune response in the vascular wall. This involves cell migration into and within the vessel wall, cell proliferation as well as accumulation of lipids in the vessel ...
Computational prediction of antisense oligonucleotides and siRNAs
(2005-09-02)
Two popular gene knockdown methods, antisense oligonucleotides (AOs) and short interfering RNAs (siRNAs) are commonly used to selectively inhibit gene expression (gene knockdown). This is an extremely valuable tool for ...
Acute pain in pedatric patients : aspects of pain management and pain assessment
(2004-11-18)
Despite advances in pain management, children's pain continue to be frequently unrecognized, dismissed and ineffectively managed while children are hospitalized. The overall purpose of this thesis was to evaluate and improve ...
On testosterone during alcohol withdrawal in men : effects on mood and insulin-like growth factor 1
(2004-11-17)
The decrease of testosterone levels after alcohol ingestion is seen in
both non-alcoholic and alcohol dependent patients. Mood effects during
hangover and alcohol detoxification are common symptoms. In ageing men ...
Pleurodesis in chronic effusions : studies on inflammatory mediators, respiratory function, predictability of treatment outcome, drug efficiency and survival after treatment
(2004-09-17)
Metastatic or primary (mesothelioma) malignancy of the pleura often
generates major pleura] effusion, giving respiratory distress and low
quality of life to the patients. Evacuation of fluid by thoracocentesis
gives ...
The impact of estrogens on leukocyte function in remodeling of extracellular matrix
(2005-11-23)
ERalpha agonist PPT (4,4',4"-(4-Propyl-[lII]-pyrazole-1,3,5 -triyl)trisphenol) and the selective ERbeta agonist DPN (2,3bis(4hydroxyphenyl)-proprionitrile) on gene expression profiles in a rat animal model. This study reports the identification of genes...
Wnt signalling in the development of ventral midbrain dopaminergic neurons
(2004-12-24)
, decreased the number of TH positive neurons, while Dkk-2 increased the conversion of Nurr1 positive precursors into DA neurons. LRP-6 null mutant mice showed a delay in DA differentiation, with 50% less DA neurons at E11.5 and a 25% reduction at E13.5. Our...
Application of nuclear medicine methods in patients with breast cancer
(2005-04-29)
While physical examination, mammography and aspiration cytology or core biopsy form the basis in the diagnosis of breast cancer, additional examinations are sometimes required in the evaluation of unclear breast masses. ...
Prevention and treatment of hepatitis B virus infection
(2005-05-06)
Despite 25 years of effective vaccines and availability of treatment options for 15 years, hepatitis B virus (HBV) infections continue to be a major global health problem. In Sweden, selective screening and vaccination ...