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Endothelin and nitric oxide in the fetoplacental circulation
(2004-05-21)
Background: Normal fetal growth and development depend on a satisfactory uteroplacental and fetoplacental blood flow. This will ensure an adequate gaseous exchange and nutritional supply to the fetus. The importance of ...
Occupational exposure to electromagnetic fields and chronic diseases
(2003-11-21)
This thesis consider two exposures from the electromagnetic spectrum extremely low-frequency magnetic fields (ELF MF) and ultraviolet (UV) radiation. ELF MF are the lowest and UV radiation ranges among the highest frequencies ...
Experimental design of phenotyping probe drugs with emphasis on CYP1A2 : their use in studies on genetic and environmental regulation of drug metabolism
(2003-05-02)
=0. 82) and the urinary ratio of N-3-demethylated metabolites / caffeine collected for 8 or 24 hours (rs=0.63-0.70). The use of a 36-hour caffeine abstinence period was appropriate to avoid the influence of caffeine ingested before the study...
Studies on the atypical orphan receptor SHP
(2001-11-23)
Nuclear receptors (NRs) comprise the largest family of transcription factors in eukaryotes and play critical roles in nearly every aspect of vertebrate development and adult physiology. In general, they function as ...
Endocrine aspects of obesity and weight reduction by bariatric surgery : with special emphasis on beta cell function
(2003-09-11)
Severe obesity is the most predictive acquired risk factor for the development of type 2 diabetes. Bariatric surgery induces marked weight loss and reverses the diabetic state significantly. This could be explained not ...
New micromanipulative techniques in reproductive biology
(2003-05-07)
New micro manipulative techniques have facilitated development to help patients who suffer from infertility and spontaneous abortion, as well as those who carry severe genetic diseases and have risks of delivering an ...
A UDP-glucose deficient mutant cell line as a model to study the cytotoxicity of Clostridium perfringens PLC
(2001-11-09)
A Chinese Hamster fibroblast mutant cell line, deficient in UDP-glucose (UDP-Glc) and hypersensitive to Clostridium perfringens phospholipase C (PLC) was used in this study to determine some of the molecular consequences ...
Studies on human polyomavirus infection in immunosuppressed patients with polyoma related tumors
(2001-09-21)
Polyomaviruses are potentially oncogenic viruses, found in humans, in other mammals and in birds all over the world. The polyomaviruses that have been observed in humans are BK virus (BKV) and JC virus (JCV) as well as the ...
Radiologic diagnosis of appendicitis in children
(2004-04-23)
Suspected appendicitis is the most common cause of emergency abdominal surgery in children. Because of the often atypical clinical findings, the diagnosis of appendicitis is difficult and may be delayed. Perforation has ...
Cholangiocarcinoma in primary sclerosing cholangitis
(2001-10-05)
Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease of unknown causes closely associated with ulcerative colitis. PSC is a progressive disease leading to liver failure and need for liver transplantation. ...