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Toxin production in clostridium difficile
(2004-05-20)
Clostridium difficile is a is a Gram potential human pathogen. It causing symptoms ranging from mild C. difficile associated diarrhea (CDAD) to severe inflammation of the colon including pseudomembranous colitis and fulminant ...
Nestin regulation in the embryonic and adult CNS
(2001-11-09)
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Furthermore we analyzed the elements required for regulation of nestin expression in the adult CNS. A 714-bp region from the second intron of the human nestin gene, which is sufficient to control embryonic expression, did not yield expression in the neurogenic...
Myocardial protection by hyperoxia
(2002-05-02)
Oxygen is essential for normal respiration in aerobic organisms, and prolonged deficit of oxygen always has detrimental consequences.However, all aerobic life forms are faced with the threat of oxidation from molecular ...
Mass spectrometry in the search for new drugs of abuse : method development and clinical application
(2004-02-27)
clinic. Novel findings included zopiclone, zolpidem, zaleplone,
N-benzylpiperazine and 1-phenyl-2-butylamine. MDMA was the most common
finding followed by zopiclone. In samples from methadone patients only
the hypnotics could be detected. Similarly...
HIV-1 infection in Tanzania : HIV antibody testing strategies and lymphocyte subset determinations
(2003-04-16)
for confirmation of HIV seropositivity were evaluated using combinations of screening assays. Wellcozyme recombinant, Organon Vironostika, Abbott recombinant and Enzygnost anti-HIV-1/2 enzyme-linked immunosorbent assays (ELISAs) and two simple/rapid assays, HIV...
Studies on uptake and effect of triclosan on production of inflammatory mediators in human gingival fibroblasts
(2003-11-21)
Triclosan (2,4,4'-trichloro-2'-hydroxy-diphenyl ether) is a lipid soluble anti-bacterial agent widely used in dentifrices, mouthrinses, soap and cosmetics. Although reports on the efficacy of triclosan on periodontal diseases are conflicting...
Blood pressure in acute ischaemic stroke : blood pressure and stress in the acute phase of stroke and influence of initial blood pressure on stroke-outcome
(2003-11-07)
) or 2mg/hour (high-dose) i.v. nimodipine (n=94) for 5 days followed by oral treatment for 16 days in a double blind manner. Thirty patients were excluded from the analysis (n=8 in placebo, 8 and 14 in low-dose and high-dose group respectively...
Adaptation to ischemia with special emphasis on nitric oxide
(2001-08-31)
Nitric oxide (NO) may play an essential role for maintenance of cardiac function and perfusion. Endothelial dysfunction of atherosclerotic vessels may aggravate cardiac ischemia/reperfusion injury. Adaptation to ischemia ...
Bioactive peptides and proteins in disease
(2004-05-17)
. ApoCIII and TTR were isolated from sera of newly diagnosed type 1 diabetic patients based on a biological assay of increases of intracellular Ca2+. The exposure of the pancreatic beta-cell to apoCIII not only increases intracellular Ca2+, but also...
Radiologic diagnosis of appendicitis in children
(2004-04-23)
Suspected appendicitis is the most common cause of emergency abdominal surgery in children. Because of the often atypical clinical findings, the diagnosis of appendicitis is difficult and may be delayed. Perforation has ...