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Genetic studies of susceptibility to diabetes mellitus with emphasis on type 1 diabetes
(2003-05-02)
11-q13 region was selected for sequencing and the variations found were analysed.
Two haplotypes formed by SNPs in ISL1 were negatively associated with T1DM in Swedish families (p<0.02). Since the genetic risk to T1DM is likely due to interaction...
Vibro cholerae O139 : identification, characterization and vaccine strategies
(2003-10-24)
Cholera is an acute dehydrating diarrheal disease, and epidemics as well as pandemics of cholera are a major health problem in developing countries and cause many deaths each year, especially in children. Cholera is caused ...
The use of mass spectrometry and DNA technology in the investigation of hemoglobin disorders
(2003-03-07)
Hemoglobin (Hb) disorders, which severely affect nearly 300,000 newborns every year, have become a global problem. The disorders manifest a wide spectrum of clinical symptoms ranging from asymptomatic to lethal conditions. ...
Receptor use of primate lentiviruses
(2003-03-21)
Human and simian immunodeficiency viruses (HIV and SIV) enter target cells using CD4, the primary cell surface receptor and a secondary receptor, called coreceptor. Coreceptor use of HIV can be related to other biological ...
Hepatitis C virus kinetics during antiviral treatment
(2004-03-05)
It is estimated that 170 million individuals have chronic hepatitis C virus (HCV) infection, whereof 20-30% will develop end stage liver disease within 20-30 years. Antiviral therapy can stop this deterioration and clear ...
The human placenta : an angiographic study
(2003-04-25)
The arterial vessels from the umbilical cord spreading over the chorion and its cotyledonary branches constitute the main body of the placental vascular tree. In the present study it was visualized by angiography and related ...
Observations on essential biochemical data profile in connection with restorative proctocolectomy in humans : vitamin B12 and fat absorption cited
(2001-10-18)
PATIENTS: The material includes 99 patients who consecutively received
handsawn pouch and ileoanal anastomosis, after mucosectomy. Sixty-five
patients were men and forty-four were women. The mean-age was 31.4 (range
17-59) ...
Quality of life in patients with malignant blood disorders : a clinical and methodological study
(2002-10-25)
The overall aim of this thesis was to evaluate and, improve measurements of, health-related quality of life (HRQL) in patients with malignant blood disorders. Patients undergoing autologous stem cell transplantation (SCT), ...
Local recurrence after breast conserving surgery in breast cancer
(2002-08-30)
The general aim of this thesis was to gain increased insight into the problem of local recurrences after breast conserving surgery for breast cancer. In a population-based cohort of 4,694 women with invasive breast cancer, ...
Digital intraoral radiography : determination of technical properties and application evaluations
(2002-05-03)
Digital registration of intraoral radiographs was introduced about 1990. One of the first systems on the market was the Sens-A-Ray (Regain Medical Systems AB, Sundsvall, Sweden). At the time of the introduction, it was ...